Protein Alignment: mEFTu1 and TUFM

• Sequence 1: NP_001163144.1
• Gene: mEFTu1
• FlyBaseID: FBgn0024556
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_003312.3
• Gene: TUFM
• HGNCID: 12420
• Length: 455
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 280/450 (62%)
• Similarity: 353/450 (78%)
• Gaps: 4/450 (1%)

  Fly    27 MSSARMLRMAGATATSTACKDWQRNGLLAAPRTGNMQQYLREYANE-KKVFERTKPHCNVGTIGH 90
            |::|.:||.....:...|.:.:...|||...:...:....|..|.| ||.:.|.|||.|||||||
Human     4 MAAATLLRATPHFSGLAAGRTFLLQGLLRLLKAPALPLLCRGLAVEAKKTYVRDKPHVNVGTIGH 68

  Fly    91 VDHGKTTLTAAITKVLADKQLAESKKYNEIDNAPEEKARGITINVAHVEYQTETRHYGHTDCPGH 155
            ||||||||||||||:||:...|:.|||.||||||||:|||||||.|||||.|..|||.|||||||
Human    69 VDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITINAAHVEYSTAARHYAHTDCPGH 133

  Fly   156 ADYIKNMITGTAQMDGAILVVAATDGAMPQTREHMLLAKQIGIDHIVVFINKVDAA-DEEMVDLV 219
            |||:||||||||.:||.||||||.||.|||||||:|||:|||::|:||::||.||. |.|||:||
Human   134 ADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQIGVEHVVVYVNKADAVQDSEMVELV 198

  Fly   220 EMEIRELLTEMGYDGDKIPVVKGSALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLL 284
            |:||||||||.||.|::.||:.||||||||.:.||:|.:::.|||..||::||.|.|:|:|||||
Human   199 ELEIRELLTEFGYKGEETPVIVGSALCALEGRDPELGLKSVQKLLDAVDTYIPVPARDLEKPFLL 263

  Fly   285 PVENVYSIPGRGTVVTGRLERGVVKKGMECEFVGYNKVLKSTVTGVEMFHQILEEAQAGDQLGAL 349
            |||.|||:|||||||||.||||::|||.|||.:|::|.:::.|||:||||:.||.|:|||.||||
Human   264 PVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSKNIRTVVTGIEMFHKSLERAEAGDNLGAL 328

  Fly   350 VRGVKRDDIKRGMVMCKPGSVKALDQLEAQVYILSKDEGGRTKPFMSFIQLQMFSRTWDCAVQVQ 414
            |||:||:|::||:||.||||:|...::|||||||||:||||.|||:|.....|||.|||.|.::.
Human   329 VRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRII 393

  Fly   415 I-PDKEMVMPGEDTKLILRLIRPMVLEQGQRFTLRDGNLTLGTGVVTSTLPPLTESQRS 472
            : |:||:.|||||.|..|.|.:||:||:||||||||||.|:|||:||:|| .:||.:::
Human   394 LPPEKELAMPGEDLKFNLILRQPMILEKGQRFTLRDGNRTIGTGLVTNTL-AMTEEEKN 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	266/392 (68%)
		EF_Tu	81..274	CDD:206671	139/194 (72%)
		EFTU_II	282..368	CDD:293898	59/86 (69%)
		mtEFTU_III	371..462	CDD:294005	56/92 (61%)
TUFM	NP_003312.3	SelB	50..444	CDD:332589	267/395 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0050
Hieranoid	1	1.000
Homologene	1	1.000				H2490
Inparanoid	1	1.050	561	1.000	Inparanoid score	I1078
Isobase	1	0.950		0	Normalized mean entropy	S366
OMA	1	1.010
OrthoDB	1	1.010				D298219at33208
OrthoFinder	1	1.000				FOG0003422
OrthoInspector	1	1.000				T1072224
orthoMCL	1	0.900				OOG5_126954
Panther	1	1.100			LDO	PTHR43721
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R370
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.860