Protein Alignment mEFTu1 and eEF2

DIOPT Version :9

• Sequence 1: NP_001163144.1
• Gene: mEFTu1 / 44438
• FlyBaseID: FBgn0024556
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 108/560 - (19%)
• Similarity: 179/560 - (31%)
• Gaps: 229/560 - (40%)

  Fly    84 NVGTIGHVDHGKTTLTAAITK---VLADKQLAESKKYNEIDNAPEEKARGITIN----------- 134
            |:..|.||||||:|||.::..   ::|..:..|::   ..|...:|:.|.|||.
  Fly    21 NMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETR---FTDTRKDEQERCITIKSTAISMYFEVE 82

  Fly   135 ------VAHVEYQTETRHYGH----TDCPGHADYIKNMITGTAQMDGAILVVAATDGAMPQTRE- 188
                  :.|.: |.|....|.    .|.|||.|:...:.......|||::||....|...||..
  Fly    83 EKDLVFITHPD-QREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETV 146

  Fly   189 -HMLLAKQIGIDHIVVFINKVDAADEEM-VDLVEM--------------------------EIR- 224
             ...:|::|   ..::|:||:|.|..|: :|..|:                          |:|
  Fly   147 LRQAIAERI---KPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYNDDGGPMGEVRV 208

  Fly   225 --------------------ELLTEMGYDGDKIPVVK--------------------------GS 243
                                :..:||..:..||.|||                          ..
  Fly   209 DPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKIDVVKLMNRLWGENFFNAKTKKWQKQKEADNKR 273

  Fly   244 ALC-------------ALEDKSPEIGK------------------EAILK------------LLQ 265
            :.|             .:..|..|||.                  :|:||            |||
  Fly   274 SFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQ 338

  Fly   266 EVDSFIPTPV------REL-------------------DKPFLLPVENVYSIPGRGTVVT-GRLE 304
            .:...:|:||      .|:                   |.|.::.:..:.....:|.... ||:.
  Fly   339 MIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVF 403

  Fly   305 RGVVKKGMECEFVG-----------YNKVLKSTVTGVEMFHQILEEAQAGDQLGALVRGVKRDDI 358
            .|.|..|.:|..:|           |.|.::.|:..:..:.:.:|:..:|:..|.:  ||.:..:
  Fly   404 AGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLV--GVDQFLV 466

  Fly   359 KRGMVMCKPGSVKALDQLEAQVYILSKDEGGRTKPFMSFIQLQMFSRTWDCAVQVQIPDKEMVMP 423
            |.|.:.    :.|....::...:.:|.                        .|:|.:..|.   |
  Fly   467 KTGTIT----TFKDAHNMKVMKFSVSP------------------------VVRVAVEPKN---P 500

  Fly   424 GEDTKLILRLIR-----PMVL----EQGQRFTLRDGNLTL 454
            .:..||:..|.|     |||.    |.|:......|.|.|
  Fly   501 ADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHL 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	108/560 (19%)
		EF_Tu	81..274	CDD:206671	67/332 (20%)
		EFTU_II	282..368	CDD:293898	18/97 (19%)
		mtEFTU_III	371..462	CDD:294005	18/93 (19%)
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	108/560 (19%)
		EF2	20..236	CDD:206672	50/221 (23%)
		EF2_snRNP_like_II	380..474	CDD:293901	18/99 (18%)
		EF2_snRNP_III	489..560	CDD:293918	16/79 (20%)
		aeEF2_snRNP_like_IV	560..732	CDD:238839
		eEF2_snRNP_like_C	728..807	CDD:239763

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840