Protein Alignment Rab18 and RAB13

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_002861.1
• Gene: RAB13 / 5872
• HGNCID: 9762
• Length: 203
• Species: Homo sapiens
• Alignment Length: 187
• Identity: 74/187 - (39%)
• Similarity: 109/187 - (58%)
• Gaps: 10/187 - (5%)

  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67
            |...|||:||:|||||:.||.||.|:.|:..:..|||:|||.:.:.::|...|:.:|||||.|||
Human     6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQERF 70

  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAI--IVVGNKIDEE--RVVD 128
            :::|.::||.|:|.|||||||...|...::.|   :.|..:|.:..:  :::|||.|.|  |.|.
Human    71 KTITTAYYRGAMGIILVYDITDEKSFENIQNW---MKSIKENASAGVERLLLGNKCDMEAKRKVQ 132

  Fly   129 REEGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIV---SSEYFNNGNASAGLDI 182
            :|:..|.||:|...|.|||||....|.:.|..:...|:   ......|||.....|:
Human   133 KEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDL 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	68/162 (42%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	70/168 (42%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		9/16 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		4/17 (24%)