Protein Alignment pie and phf6

DIOPT Version :10

• Sequence 1: NP_524740.2
• Gene: pie / 44315
• FlyBaseID: FBgn0005683
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001107695.1
• Gene: phf6 / 779543
• XenbaseID: XB-GENE-999439
• Length: 363
• Species: Xenopus tropicalis
• Alignment Length: 310
• Identity: 72/310 - (23%)
• Similarity: 117/310 - (37%)
• Gaps: 83/310 - (26%)

  Fly     4 NKELQCLICKYSDTDDLVFGEWMIVRNLQV--HYFCLLLSTHLPQRGGDSSGILGFLLRDIREEA 66
            |:|.:|             |:.:|..|.:|  |:.|:|.|:.|.....||..:.||.:.||::|.
 Frog    23 NREKEC-------------GQLLISSNQKVAAHHRCMLFSSALVSSQSDSENLGGFSIEDIQKEL 74

  Fly    67 AAAEKRKCWYCNKIGASLQCD--RCRSLFHLKCGLENRAVFE---FCGQYKSYCYKCRPMDDYKR 126
            ....|..|..|:..||::.||  .|...:|..|.|.::|..:   ..|.|..:|.|      :|.
 Frog    75 KRGRKLMCSLCHCPGATIGCDVKSCHRTYHYHCALRDKAHIQENPSQGMYTIFCRK------HKE 133

  Fly   127 QLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHK----KCMRQYALTSGYYLRCIWCRS 187
            |:|::..               ||.    |...|.|.|.:    :..|..:.||         .|
 Frog   134 QVQNSDD---------------ELE----GSFTRRGLAPQRGRGRGSRGKSRTS---------NS 170

  Fly   188 ERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNC-LCPSGRTYNRLSWVILCCSSC 251
            ....:..||.|:...:..   |...:..|..|..:....:|.| .|.:|...|.....:...::.
 Frog   171 RGQSEESRLSSLHCTEET---ESSSSRDRSPHRSSPSDTRPKCGFCHAGDEENETRGKLHVFNAK 232

  Fly   252 AATSAHLKCLV---GALRL--PKKRERTDF---------------KCSMC 281
            .| :||.||::   |.::|  ..:.|..||               ||::|
 Frog   233 KA-AAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVIQEMKRGKRMKCTLC 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_524740.2	PHD_SF	9..117	CDD:473978	32/114 (28%)
		PHD_SF	224..>260	CDD:473978	8/36 (22%)
		PRK10263	<265..>493	CDD:236669	7/34 (21%)
phf6	NP_001107695.1	ePHD1_PHF6	17..131	CDD:277180	35/126 (28%)
		ePHD2_PHF6	210..327	CDD:277181	17/73 (23%)