Protein Alignment pie and phf11

DIOPT Version :10

• Sequence 1: NP_524740.2
• Gene: pie / 44315
• FlyBaseID: FBgn0005683
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_021334650.1
• Gene: phf11 / 569187
• ZFINID: ZDB-GENE-081104-417
• Length: 531
• Species: Danio rerio
• Alignment Length: 520
• Identity: 118/520 - (22%)
• Similarity: 185/520 - (35%)
• Gaps: 153/520 - (29%)

  Fly     9 CLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDS-SGILGFLLRDIREEAAAAEKR 72
            |.:||.||..:.. |......::..|..|||.|:::..:...: ..:.||.|.|:::|....:|.
Zfish    14 CALCKTSDETETT-GPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKL 77

  Fly    73 KCWYCNKIGASLQCD--RCRSLFHLKCGL--ENRAVFEF-CGQYKSYCYKCRP--------MDD- 123
            :|::|||.||::.|:  ||...||..|.:  :.||:.:| .|.|:.||....|        :|:
Zfish    78 RCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDND 142

  Fly   124 -------------YKRQLQSNPPRNATCPICFSSIYKVELHCVVYG----DCCRLGFAHKKCMRQ 171
                         .::..||.|....|.|   |...|........|    |....|.|.|
Zfish   143 VDLVLASVEKHVPAEQHNQSTPDPERTRP---SEEVKTPAKASSNGGLTSDQRSCGTADK----- 199

  Fly   172 YALTSGYYLRCIWCRSE----------RFRDSIRLQSVFVPDR------DATWEKQRNAYRELHE 220
                     |.|.|.|:          :.:...||:   .||.      ||....:.:|    .|
Zfish   200 ---------RRIECDSQEHSPEHKTPTKKKKKRRLE---YPDNENPTSADAVMAPEVSA----PE 248

  Fly   221 RNLKCDQPNCLCP---SGRTYNRLSWVILCCSSCAATSAHLKCLVGALRLPKKRERTDFKCSMCL 282
            .::..:|||...|   :.|:..:|:   |..:..||..              :.:.||.: |:.|
Zfish   249 ESMTVNQPNHSTPLPENTRSCEKLN---LSTTGAAADD--------------EDDETDIE-SVSL 295

  Fly   283 DV-----ERRIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATRSLTQTPVFSEEDESERSSN 342
            .|     .|.|.|..:..|.||:                 |......|...|....|...|..|
Zfish   296 SVLNKTHLRHIEESQSVLTYETD-----------------PVPCIVILDSGPSLESEISLESCS- 342

  Fly   343 ITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASP--KTSIDENHSPQPIA--RRDTSDSPQ 403
                             |.:|......|.:|...:.:|  :||..:..:||..|  ::..||.|
Zfish   343 -----------------SRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGP- 389

  Fly   404 PIAASEIPDSPQPTAA---SEIPDLPQTTAINVN------PELTQQTALNTIPHSPQPEASFSTQ 459
                |..|..|.|||.   |.:..|.| :||...      .|::...:.:|:|:.....|.|.|:
Zfish   390 ----SVSPQHPSPTAGLRISAVCTLAQ-SAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTR 449

  Fly   460  459
            Zfish   450  449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_524740.2	PHD_SF	9..117	CDD:473978	36/113 (32%)
		PHD_SF	224..>260	CDD:473978	9/38 (24%)
		PRK10263	<265..>493	CDD:236669	47/213 (22%)
phf11	XP_021334650.1	ePHD_PHF6_like	14..128	CDD:277143	36/114 (32%)
		Herpes_BLLF1	<228..445	CDD:282904	59/279 (21%)