DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pie and si:ch211-165g14.1

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_689373.2	Gene:	si:ch211-165g14.1 / 560882	ZFINID:	ZDB-GENE-131127-601	Length:	672	Species:	Danio rerio

Alignment Length:	345	Identity:	73/345 - (21%)
Similarity:	116/345 - (33%)	Gaps:	99/345 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 SSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLDVERRIAEGPARTTEETNADGDNQ-----VD 308
            ||.||.:.|        ......|:|        .:|...:|....:||.|::|.|:.     |.
Zfish   175 SSAAANTLH--------STSSAAEQT--------AIETLASECTKTSTESTSSDADSDIIEVPVS 223

  Fly   309 GSFYVQK--LGP--------DAATRSLTQTPVFSEEDESERSS----NIT-------VIFSQPKS 352
            .|....:  |.|        |.:.|:|..:.:..:.|...:.:    |:.       .:|.....
Zfish   224 NSRCTTRPNLRPRPTSVIVSDTSGRTLRSSRLKQQVDADHQMNFSPKNVNSVYTMDEAVFETANH 288

  Fly   353 NATSERLSLSPPQEEMIVEIPDSPEAS------------PKTSIDENHS--PQPIARRDTSDSPQ 403
            ...||..||....|.::  ||.|||.|            |.||..||.|  ..|..||.:|.:|.
Zfish   289 RVGSESKSLLSWMESVL--IPISPEDSEQDTNSSFPKNFPSTSDAENSSILRSPENRRSSSSTPS 351

  Fly   404 -----PIAASEIPDSPQPTAASEIPDLP--QTTAINVNPELTQQTALNTIPHSPQPEASFSTQLV 461
                 |.:.|.....|:|....:....|  |.......|:.|::..... |....|.:.||
Zfish   352 HQERTPPSKSRKRAKPRPKPRPKPRPKPKKQPKRAAPGPKTTKKRRRRK-PQPSGPSSMFS---- 411

  Fly   462 SQTFDCPQPQEQAV-AKAPNSPSLPKEDPNTLLVLKSGFQCPGEPFFYLVIYEFEHGTCMGECIG 525
                    |:|..: .|..|..|..||       :::...|      ::.....|..:|
Zfish   412 --------PKEPEIKLKFANHKSEKKE-------VRTAVHC------FVPYIRMEFSSC------ 449

  Fly   526 TCVLRFKEDDPRIQDTSQAA 545
             .::.|:|::...:..||.|
Zfish   450 -TIVNFREEEVASKKGSQLA 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600
		PHD_SF	224..>260	CDD:304600	5/10 (50%)
		PARM	318..>491	CDD:293666	48/213 (23%)
si:ch211-165g14.1	XP_689373.2	PHD_SF	496..657	CDD:304600
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900