Protein Alignment SoxN and sox1

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001074465.1
• Gene: sox1 / 779569
• XenbaseID: XB-GENE-1018269
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 438
• Identity: 172/438 - (39%)
• Similarity: 202/438 - (46%)
• Gaps: 112/438 - (25%)

  Fly   130 SHQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQR 194
            |....|.....|.|.....|.     |||...|..|.          ||||||||||||||||||
 Frog     3 SMMMETDLHSPGVQPPSNTGQ-----TGGGGGNKANQ----------DRVKRPMNAFMVWSRGQR 52

  Fly   195 RKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTK 259
            ||||.:|||||||||||||||:||.:||:||||||||||||||:|||||||||||||||||||.|
 Frog    53 RKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK 117

  Fly   260 TKEKYPM-GGLMPGQTVGGGAPGEPVTPTRVQGQPG----QNQSLNGSGGSA------------- 306
             |:||.: |||:  ...|||..|..::|....|..|    |.....|||.||
 Frog   118 -KDKYSLAGGLL--HAAGGGHMGVGLSPGGGGGGTGGVVVQRLESPGSGASAGGYAHMNGWANGA 179

  Fly   307 ---AAAAAAAAAAAQQAR----QDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHY----- 359
               :.|||||||..|:|:    |...|.....|:.|:.:..|       .:...:...|:
 Frog   180 YPGSVAAAAAAAMMQEAQLAYSQQQQQHPGSGGHHPHHHPHH-------PHHHPHHHPHHNPTPH 237

  Fly   360 -------AAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYG----GSSLQQQPGSP 413
                   ...||||..:      .|..:.|.||       ....|||.||    .||.||..|||
 Frog   238 PPPPPPQPMHRYDMSAL------QYSPLPGAQT-------YMTASPSGYGALGYSSSQQQHQGSP 289

  Fly   414 TPYGGGGGGGGQVSCQSHSPS----DSSIKSEP-VSPSPSAIALNNNNNINNNHIMKREYSS--- 470
            :............:..:.|.:    .|.:|||| |||..|....:|......:   .||..|
 Frog   290 SSAAVAAAAAAAAAAAASSGALGALGSLVKSEPSVSPPVSGGGPHNRPPCPGD---LREMISMYL 351

  Fly   471 ---------AAAAAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQ 509
                     ||||||||||||||       ...::.||.      |||
 Frog   352 PSGGEAGDPAAAAAAAAAAAAAA-------TSRLHSLPQ------HYQ 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	67/74 (91%)
sox1	NP_001074465.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		12/49 (24%)
		HMG-box_SoxB	35..114	CDD:438790	71/78 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..249		6/58 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	320..343		8/25 (32%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	345..353		2/7 (29%)