Protein Alignment SoxN and sox3

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001007502.1
• Gene: sox3 / 493228
• XenbaseID: XB-GENE-484815
• Length: 307
• Species: Xenopus tropicalis
• Alignment Length: 379
• Identity: 140/379 - (36%)
• Similarity: 171/379 - (45%)
• Gaps: 114/379 - (30%)

  Fly   158 GSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSE 222
            |:.....|::..::     :|||||||||||||||||||||.:|||||||||||||||.||.||:
 Frog    24 GTPGGKGNASIPDQ-----ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSD 83

  Fly   223 SEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPT 287
            ||||||||||||||||||||:||||||||||||||.| |:||.    :||..:   |||  |:|
 Frog    84 SEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLK-KDKYS----LPGNLL---APG--VSP- 137

  Fly   288 RVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQT 352
                                  .|::....|  |.|.|.  ..||:....|.:..|..|.:.:..
 Frog   138 ----------------------VASSVGVGQ--RIDTYA--HMNGWTNGAYSLMQDQLGYSQHPG 176

  Fly   353 SYMGQHYAAQ-RYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQ--QPGSPSPYGGSSLQQQPGSPT 414
            ....|....| |||||              |.|.||..||.|  ...:.|.|..|....|..|..
 Frog   177 MNSPQMQQIQHRYDMG--------------GLQYSPMMSSAQTYMNAAASTYSMSPAYNQQSSTV 227

  Fly   415 PYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAA 479
            ...|..|              |.:||||.||.|:.          .:|..:
 Frog   228 MSLGSMG--------------SVVKSEPSSPPPAI----------TSHTQR-------------- 254

  Fly   480 AAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQH 533
                |..|:|..:::||..|.         .|:.|    ..|:|..:.|...||
 Frog   255 ----ACLGDLRDMISMYLPPG---------GDASD----PSSLQSSRLHSVHQH 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	67/74 (91%)
sox3	NP_001007502.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		3/21 (14%)
		HMG-box_SoxB	38..113	CDD:438790	67/74 (91%)
		SOXp	109..189	CDD:463537	33/116 (28%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	259..270		3/10 (30%)