Protein Alignment SoxN and sox2

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_998283.1
• Gene: sox2 / 378723
• ZFINID: ZDB-GENE-030909-1
• Length: 315
• Species: Danio rerio
• Alignment Length: 418
• Identity: 150/418 - (35%)
• Similarity: 188/418 - (44%)
• Gaps: 121/418 - (28%)

  Fly   156 TGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDL 220
            |||:.|.|   ::.|..:...||:|||||||||||||||||||.:|||||||||||||||:||.|
Zfish    18 TGGTGNTN---SSGNNQKNSPDRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLL 79

  Fly   221 SESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPM-GGLMPGQTVGGGAPGEPV 284
            |||||||||||||||||:|||||||||||||||||||.| |:||.: |||:        |||
Zfish    80 SESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMK-KDKYTLPGGLL--------APG--- 132

  Fly   285 TPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAA 349
                            |:|..|.....|...|....|.|.|.  ..||:...||.|..:..|...
Zfish   133 ----------------GNGMGAGVGVGAGLGAGVNQRMDSYA--HMNGWTNGGYGMMQEQLGYPQ 179

  Fly   350 YQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPT 414
            :.:  :..|..||...| |.|:.....|.:::..||       ...|||:.....|.|..||...
Zfish   180 HPS--LNAHNTAQMQPM-HRYDMSALQYNSMTNSQT-------YMNGSPTYSMSYSQQSTPGMTL 234

  Fly   415 PYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAA 479
                  |..|.|           :|||. |.||..:..::::.
Zfish   235 ------GSMGSV-----------VKSES-SSSPPVVTSSSHSR---------------------- 259

  Fly   480 AAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQQ 544
             |.....|:|..:::||               .|..:.|.||.|.      :.|:||.:|..|..
Zfish   260 -AGQCQTGDLRDMISMY---------------LPGAEVQDQSAQS------RLHMSQHYQSAPVP 302

  Fly   545 HHTMQQQQQQHHLQHQQSLRAMAPLAHM 572
            ..|               :....||:||
Zfish   303 GTT---------------INGTIPLSHM 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	68/74 (92%)
sox2	NP_998283.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		9/25 (36%)
		HMG-box_SoxB	36..115	CDD:438790	72/78 (92%)
		SOXp	107..197	CDD:463537	39/122 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..263		10/62 (16%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	270..278		2/22 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..315		5/33 (15%)