Protein Alignment SoxN and Sox18

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001019952.1
• Gene: Sox18 / 311723
• RGDID: 1311718
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 90/302 - (29%)
• Similarity: 137/302 - (45%)
• Gaps: 83/302 - (27%)

  Fly   173 QQHAD--RVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRL 235
            :|.||  |::|||||||||::.:|:::|..||.:||:.:||.||..||:|:.:|||||::||:||
  Rat    71 RQTADELRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEKRPFVEEAERL 135

  Fly   236 RAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLN 300
            |..|:::||:|||||||| |...|.:...| |.|:|| .|...||.||.
  Rat   136 RVQHLRDHPNYKYRPRRK-KQARKVRRLEP-GLLLPG-LVQPSAPPEPF---------------- 181

  Fly   301 GSGGSAAAAAAAAAAAAQQARQ------DMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHY 359
                      |||:.:|:..|:      :...:..|.   |....:....:|.|::....:....
  Rat   182 ----------AAASGSARSFRELPTLGAEFDGLGLPT---PERSPLDGLESGEASFFPPPLAPED 233

  Fly   360 AAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQ------PGSP--SPYGGSSLQQQPGSPTPY 416
            .|.|     .:...||  ..::...:..|||||.:      |.:|  ..|.|:.     |:|.|:
  Rat   234 CALR-----AFRAPYA--PELARDPSFCYGSSLAEALRTAPPAAPLAGLYYGTL-----GTPGPF 286

  Fly   417 GGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNI 458
                                   ..|:||.|.|.:|.....:
  Rat   287 -----------------------PNPLSPPPEAPSLEGTEQL 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	42/76 (55%)
Sox18	NP_001019952.1	HMG-box_SoxF_SOX18	76..155	CDD:438851	44/79 (56%)
		Sox17_18_mid	191..239	CDD:463454	7/55 (13%)