Protein Alignment SoxN and sox3

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001001811.2
• Gene: sox3 / 30529
• ZFINID: ZDB-GENE-980526-333
• Length: 300
• Species: Danio rerio
• Alignment Length: 385
• Identity: 141/385 - (36%)
• Similarity: 176/385 - (45%)
• Gaps: 118/385 - (30%)

  Fly   150 SALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLG 214
            |...|:|||.:|:.|:.          ||||||||||||||||||||||.:||||||||||||||
Zfish    16 SNTGSVTGGKNNSANDQ----------DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 70

  Fly   215 AQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPM-GGLMPGQTVGGG 278
            |.||.|:::||||||||||||||:|||||||||||||||||||.| |:||.: |||:
Zfish    71 ADWKLLTDAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKTKTLLK-KDKYSLPGGLL-------- 126

  Fly   279 APGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHAD 343
            |||                         |.|...|.:..|  |.|...|   ||:..:.|.:..|
Zfish   127 APG-------------------------ANAVNNAVSVGQ--RMDYTHM---NGWTNSAYSLMQD 161

  Fly   344 PAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQ 408
            ......:.:....|.....||||..:      .|..:|..||  |.::.....|.||    :..|
Zfish   162 QLAYPQHPSMNSPQIQQMHRYDMAGL------QYPMMSTAQT--YMNAASTYSSMSP----AYTQ 214

  Fly   409 QPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAA 473
            |..|..       |.|.::        |..|:||.||.|:..:                :|..|.
Zfish   215 QTSSAM-------GLGSMA--------SVCKTEPSSPPPAITS----------------HSQRAC 248

  Fly   474 AAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQH 533
            .            |:|..:::||..|.         .||.|    |.|:|..:.|....|
Zfish   249 L------------GDLRDMISMYLPPG---------GDSAD----HSSLQTSRLHSVHPH 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	66/74 (89%)
sox3	NP_001001811.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		8/28 (29%)
		HMG-box_SoxB	33..108	CDD:438790	66/74 (89%)
		SOXp	104..182	CDD:463537	32/116 (28%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	251..262		3/10 (30%)