Protein Alignment SoxN and Sox6

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_006507560.1
• Gene: Sox6 / 20679
• MGIID: 98368
• Length: 828
• Species: Mus musculus
• Alignment Length: 495
• Identity: 120/495 - (24%)
• Similarity: 176/495 - (35%)
• Gaps: 194/495 - (39%)

  Fly    30 AASPYSALAPLMNLGQSHLTHSQLS------------------H---HNHHHHHM----SAHIAA 69
            ||:..|.|:|| .|.:.|::|.|::                  |   |:::|..:    :|.:|:
Mouse   314 AAAAASGLSPL-QLQKGHVSHPQINPRLKGISDRFGRNLDPSEHGGGHSYNHRQIEQLYAAQLAS 377

  Fly    70 SQ---------SPNPLSSLQSSMANTLNGSQVGQQ--QQQQQQQQSSPLHSSSE----------L 113
            .|         :|.|.:|..:.....:...:.|..  .|.:.:..:.||:.||.          .
Mouse   378 MQVSPGAKMPSTPQPPNSAGAVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPT 442

  Fly   114 SPTQ----------------SSIGS---------------HHMTSPV--------------SHQQ 133
            ||||                |||.|               ..:.||.              :.:.
Mouse   443 SPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKM 507

  Fly   134 HTQQQQHGQQQHLGAGSALSS------------------------LTGGSSNNN----------- 163
            ..|.|:..|||..|....|||                        |||.||.:.
Mouse   508 REQIQREQQQQPHGVDGKLSSMNNMGLSNCRTEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTR 572

  Fly   164 ----------NNSATANKNQQH-------------------------ADRVKRPMNAFMVWSRGQ 193
                      |.||.  |.||:                         ...:||||||||||::.:
Mouse   573 PEDAEGSKAMNGSAA--KLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDE 635

  Fly   194 RRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLT 258
            |||:....|.||||.|||.||::||.:|..||:|:.:|..||..:|::::|:|||:||.| :|..
Mouse   636 RRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK-RTCI 699

  Fly   259 KTKEKYPMG---GLMPGQ--------TVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAA 312
            ...:|..:|   .||..:        || |..|..|:|.......||             |...|
Mouse   700 VDGKKLRIGEYKQLMRSRRQEMRQFFTV-GQQPQMPITTGTGVVYPG-------------AITMA 750

  Fly   313 AAAAAQQARQDMYQMNA-PNGYMP---NGYMMHADPAGAA 348
            ....:.|...|....:| |...:|   :.|.|..|.|..|
Mouse   751 TTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGASLA 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	38/74 (51%)
Sox6	XP_006507560.1	HMG-box_EGL13-like	619..696	CDD:438848	40/77 (52%)