Protein Alignment Rs1 and ddx10

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_001922220.1
• Gene: ddx10 / 569118
• ZFINID: ZDB-GENE-071022-2
• Length: 864
• Species: Danio rerio
• Alignment Length: 847
• Identity: 233/847 - (27%)
• Similarity: 363/847 - (42%)
• Gaps: 201/847 - (23%)

  Fly    37 LRHKKVTEFEKGFEFVSSVKEYNQDTWDDLMKYVKRKARTKTDDKIAARLQKRGGAEAVAAEQSD 101
            :|.|||.|          ......|...:..|:.|:.|:|||..|   |.||
Zfish     1 MRDKKVKE----------KTNITDDPVKNFEKWKKKYAKTKTKVK---RSQK------------- 39

  Fly   102 GSEIDLSEDELKHDNLRLREKKESKKKKKKAGEEDEEDEGEKMQFADTVEANEQITSFYQMNLSR 166
             |::...:.|::.:|:           ||...:..|.:..|.::|:|             ..||:
Zfish    40 -SKVKKRDWEVERENI-----------KKLVDKYSEINPKEAVKFSD-------------FPLSK 79

  Fly   167 PLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITR 231
            ..::.:....|..||.||..||..||.|||:.|.|.||:|||.|:::|.|| .|||    :..|.
Zfish    80 KTLKGLLEAQYRQPTEIQRQTIGFALQGRDVLGAAKTGSGKTLAFLIPVLE-CLYR----EQWTA 139

  Fly   232 V-----LVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQ-EAVLRQNPDIVIATPGRL 290
            :     |::.|||||..|.::|.:::.:......||.|||.|:|.: |.:.|.|  |:|.|||||
Zfish   140 MDGLGALIISPTRELAYQTFEVLRKVGKNHEFSAGLVIGGKDLKDESEKIHRTN--IIICTPGRL 202

  Fly   291 IDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKDLAAV 355
            :.|:..|.:|....:.:|:||||||:||..||:.:..|:.:..|:|||:|||||.:..|||||.:
Zfish   203 LQHMDETATFHASDLHMLVLDEADRILDMGFADTLNAIVENLPKSRQTLLFSATQTRSVKDLARL 267

  Fly   356 SLDKPIKVFVNNNQQVAFN----LRQEFIRIREDKEGDREPILASLICRTFHDHCMVFVQTKKQA 416
            ||..|..|:|  ::|..|:    |.|.::.....::.:   :|.|.:........:||....|:.
Zfish   268 SLKDPEYVWV--HEQAKFSTPATLEQNYVVCELHQKVN---MLYSFLRSHLQKKIIVFFACCKEV 327

  Fly   417 HRLHILLGLL--GVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFV 479
            ..|..:...|  |:....|||...|.:|:|....|..:...||.|||:||||||...|..|:.|.
Zfish   328 QYLFRIFCRLRPGISVLALHGKQQQMKRVEVYNDFVRKTSAVLFATDIAARGLDFPAVNWVLQFD 392

  Fly   480 MPITTEHYIHRVGRTAR--AGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIEKYRNK 542
            .|.....||||||||||  .|...:.|.|..|::..|         |.::.:.:|...|:....|
Zfish   393 CPEDANTYIHRVGRTARYKEGGEALLVLLPSEEKGMI---------SQLQEKKVPINKIQVNPEK 448

  Fly   543 LTSLEPEIQNIL--DEEQAER------------QLAKTEQQLSKTERKL------LGQTNERRGW 587
            |.|::.:::..|  ::||.||            .|.|.:......:.||      ||.....|..
Zfish   449 LMSVQQKLEAFLAQEKEQKERAQRCFVSYLRSVYLMKNKDVFDVLQLKLPEYAMSLGLAVAPRVR 513

  Fly   588 FQTKQQREAEKDRLALTTGDEDKASGG-----------------KGKGKTAGKRKRPEYGGDGED 635
            |..|.|::..      |...:|.::.|                 |.|.:.:...:..:...|.::
Zfish   514 FLLKAQQQRR------TAAQDDSSTAGHQSEDELQSFTAQLQQQKTKSEPSQSEEEEDDDDDDDE 572

  Fly   636 G----PPVKDLEAKR--------NKKKKEEPRKK-------------TPEQL---------AKER 666
            |    ..:||.::.:        |::..::.:::             ..|::         ||.|
Zfish   573 GDDDDEDIKDQDSLKPLSLLCGFNEEDDDDDQREADLLTVKCKDVFNVKEEIKDEEDADADAKNR 637

  Fly   667 AMKEIEKVSLVRAKMAKLRKRPGKLGAA---TEVHRSGASDGK-----PKRRGGQSAFTNDLTDV 723
            ..||.:   ...||  |::||..|:...   ||       |||     |..:........|..||
Zfish   638 KQKESK---FKDAK--KIQKRNLKVNTKKVFTE-------DGKVVQQWPPLQRTVVPDEEDDDDV 690

  Fly   724 SRG-----GALRLRSEANRHKKM---TKIAAKKKASSVKLTNKAGKNKFNKGKNFGGPRHAKKDK 780
            ..|     ...|||.|.....||   .||  |:|....:|..||.:.:.:|       :| |::|
Zfish   691 MTGINVEAAKERLRREDQAFDKMEYRRKI--KEKHREKRLKEKAARREASK-------QH-KEEK 745

  Fly   781 KK 782
            :|
Zfish   746 RK 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	150/447 (34%)
ddx10	XP_001922220.1	SrmB	71..471	CDD:440279	150/433 (35%)
		DEADc_DDX10	81..278	CDD:350699	86/205 (42%)
		DUF4217	453..511	CDD:464056	11/57 (19%)