Protein Alignment Rs1 and pit

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 194/688 - (28%)
• Similarity: 321/688 - (46%)
• Gaps: 113/688 - (16%)

  Fly    24 EDSDAEVEYQPTKLRHKKVTE---FEKGFEFVSSVKEYNQDTWDDLMKYVKRKARTKTD-DKIAA 84
            ||.|.|.::|...|..||..:   .::..:..:|..|.:.|..:|       :|...:| |::
  Fly    60 EDDDLEEDFQEAPLPKKKQQKQPPKKQQIQVANSDSESDDDEQED-------EADEDSDLDEV-- 115

  Fly    85 RLQKRGGAEAVAAEQSDGSE-IDLSEDELKHDNLRLREKK----ESKKKKKKAGEEDEEDEGEKM 144
                   ||....:...||| .|..|||.:.:.:..::.|    :||.:..|..::||....|..
  Fly   116 -------AEVDEEDVDSGSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESS 173

  Fly   145 QFA-DTVEANEQITSFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKT 208
            ..| |..:::::..:..:..:|...:|||..:|:...|.||:.::...|.|||:.|.|.||:|||
  Fly   174 LAALDYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKT 238

  Fly   209 AAYMLPTLE---RLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVK 270
            .|:::|.:|   :|.:.|.|.   |.|:::.|||||..|.:.|.|:|........||.:||.:.:
  Fly   239 LAFLIPAVELINKLRFMPRNG---TGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQ 300

  Fly   271 AQEAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKT 335
            .:...|.:..:|::||||||:||::|:|.|...:::.||:||.||:|:..|.|::|:|||...|.
  Fly   301 VESEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKR 365

  Fly   336 RQTMLFSATMSEQVKDLAAVSL-DKPIKVFVNNNQQVAF--NLRQEFIRIREDKEGDREPILASL 397
            |||||||||.:.:::.|:.::| .:||.|.|::||..|.  .|.|.:|....:|   |..:|.:.
  Fly   366 RQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEK---RLLVLFTF 427

  Fly   398 ICRTFHDHCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDV 462
            :.:......|||..:.......|.|...:.:....:||...|.:|..:..:|...:..:|:.|||
  Fly   428 LKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDV 492

  Fly   463 AARGLDIVGVKTVINFVMPITTEHYIHRVGRTAR-AGRAGISVSLAGEKERKIVKDIIKNAESTI 526
            |||||||..|..::.:..|.....|||||||||| :|.:|.::.|...:|...:: .:|.|:
  Fly   493 AARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLR-YLKAAK--- 553

  Fly   527 KNRIIPPEIIEKYRNKLTSLEPEIQNILD-EEQAERQLAKTEQQLSKTERKLLGQTNERRGWFQT 590
                :|          |...|...|.|.| :.|.|:.:||                    .:|..
  Fly   554 ----VP----------LNEFEFSWQKIADIQLQLEKLIAK--------------------NYFLN 584

  Fly   591 KQQREAEKD----------RLALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEAK 645
            :..:||.|.          :........|..:..|..|...               |||.||:..
  Fly   585 QSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKSFGFLV---------------PPVVDLKVG 634

  Fly   646 RNKKKKEEPR---------KKTPE-QLAKERAMKEIEK 673
            ..|:::.|.|         ||..| ..:|:|..|::.:
  Fly   635 AAKRERPEKRVGGGGFGFYKKMNEGSASKQRHFKQVNR 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	140/427 (33%)
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	79/199 (40%)
		SF2_C_DEAD	408..537	CDD:350174	41/131 (31%)
		DUF4217	570..627	CDD:464056	11/91 (12%)