Protein Alignment Rs1 and CG5800

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_573230.1
• Gene: CG5800 / 32742
• FlyBaseID: FBgn0030855
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 196/729 - (26%)
• Similarity: 317/729 - (43%)
• Gaps: 128/729 - (17%)

  Fly   115 DNLRLREKKESKKKKKKAGEEDEEDEGEKMQFADTVEANEQITSFYQMNLSRPLMRAIGVLGYIY 179
            ||.:.|.::|..|.:..|.|.:.:|  .|.::|: ::|. .|..|.|..||:...:|:....:::
  Fly    34 DNSQKRPRQEINKSRLAATEAEIQD--LKTKYAE-IDAT-AIKKFAQFPLSKKTQKALAESKFVH 94

  Fly   180 PTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQ 244
            ||.:|..:|..||.|:|:.|.|.||:|||.|:::|.||.|.....:.......:::.|||||..|
  Fly    95 PTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQ 159

  Fly   245 VYQVTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLI 309
            :::..|::.:......||.|||.::|.:...:.| .:|:|.|||||:.|:...|.|...::|:|:
  Fly   160 IFETLKKVGKHHDFSAGLIIGGKNLKFERTRMDQ-CNILICTPGRLLQHMDENPLFNTSTMEMLV 223

  Fly   310 LDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKDLAAVSLDKPIKVFVN-------- 366
            ||||||.||..|.:.:..||.:....|||:|||||.:..|:|||.::|..|:.|...
  Fly   224 LDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEP 288

  Fly   367 --------NNQQVAFN--LRQEFIRIREDKEGDREPILASLICRTFHDHCMVFVQTKKQAHRLHI 421
                    |...:|..  |:|.::.:..:   |:..:|.|.|........:|||.:.|||..|:.
  Fly   289 SASTKKTPNTAVLAVPELLQQSYVVLNLE---DKITMLWSFIKNHLKQKIIVFVASCKQAKYLYE 350

  Fly   422 LLGLLGVRAGE----LHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVMPI 482
            :...|  |.|.    |:|.|.|.:|:...:.|..:...|:.:||||:||||...|..|:....|.
  Fly   351 IFCKL--RPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPE 413

  Fly   483 TTEHYIHRVGRTAR-AGRAGISVSLAGEKERKIVKDIIKNAESTIK------NRIIPPEI-IEKY 539
            ....||||.||:|| ..|....:.|...:|..::..:.:.....|:      .::..|.: ||.:
  Fly   414 DVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDPKKLFSPRVKIEAF 478

  Fly   540 -------------------------RNK--------------------LTSLEPEIQNILDEEQA 559
                                     |||                    :|...|.::..| ..|.
  Fly   479 LAQFPELRATAQRAFLSYIKSVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPRVPFLEKFL-WRQK 542

  Fly   560 ERQLAKTEQQLSKTERKLLGQTNERRGWFQTKQQREAEKDRLALTTGDEDKASGGKGKGKTAGKR 624
            :.|..|.:...:|:...||.:.        ||||        :...||||:.:   ...:...|.
  Fly   543 QLQQQKEQGDNAKSINPLLSKL--------TKQQ--------SFGGGDEDEEN---SDDEDFIKV 588

  Fly   625 KRPEYGGDGEDGPPVKDLEAKRNKKKKEEP-----RKK--TPEQLAKERAMKEIEKVSLVR---- 678
            ||.::..:||   |||..|....:.:.|.|     |:|  |...|||:...|.::..|.::
  Fly   589 KRKDHDVEGE---PVKLDEEDDTENEAEAPLVVPKREKLVTKASLAKKALKKNLQVNSKLKFDDE 650

  Fly   679 -AKMAKLRKRPGKLGAATEVHRSGASDGKPKRRGGQSAFTND--LTDVSRGGALRLRSEANRHKK 740
             ..||..|.:...|.|..........|      ||.:...:.  ||:..:....|.|....:..|
  Fly   651 GETMADDRSQMKALSARQRTVNQDDDD------GGINLVLSKALLTEEDQYDKQRFRELVKKRHK 709

  Fly   741 MTKIAAKKKASSVK 754
            :.:...:|||...|
  Fly   710 LQREKLRKKAEEAK 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	139/494 (28%)
CG5800	NP_573230.1	SrmB	71..493	CDD:440279	129/427 (30%)
		DEADc_DDX10	83..279	CDD:350699	73/196 (37%)
		DUF4217	474..530	CDD:464056	6/55 (11%)