Protein Alignment Rs1 and Ddx49

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001108495.2
• Gene: Ddx49 / 290660
• RGDID: 1311124
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 168/526 - (31%)
• Similarity: 260/526 - (49%)
• Gaps: 84/526 - (15%)

  Fly   156 ITSFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLL 220
            :..|.::.||..|:.....||...|||:|...||..|.|||..|||.||:|||||::||.|::|.
  Rat     1 MAGFAELRLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLS 65

  Fly   221 YRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIA 285
            ..|..    ...|||.|||||..|:.:..:.|.:...:...:.:||:|:..|...|.:.|.:|||
  Rat    66 EDPYG----IFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQALELSRKPHVVIA 126

  Fly   286 TPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDE---YFAEQMKEIINSCCKTRQTMLFSATMSE 347
            |||||.||::::.:|.:..|..|:||||||:|::   .|...::.|:::....|||:|||||:::
  Rat   127 TPGRLADHLRSSNTFNMKKIRFLVLDEADRLLEQGCTDFTADLETILSAVPARRQTLLFSATLTD 191

  Fly   348 QVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFIRIREDKEGDREPILASLICRTFHDH---C--M 407
            .:|:|..::.::|.........:....|.|.::.:.|..   ::..|..|: :||.|.   |  :
  Rat   192 TLKELQGLATNQPFFWEAQATVRTVEQLDQRYLLVPEKV---KDAYLVHLV-QTFQDQLEDCSII 252

  Fly   408 VFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGV 472
            :|..|.|....|.::|.........||..:.|::|..:|.:||.....:|||||||:|||||..|
  Rat   253 IFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALARFKSSTYRILIATDVASRGLDIPTV 317

  Fly   473 KTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIE 537
            :.|||...|...:.|||||||||||||.|.:::|..:.:..:
  Rat   318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHL----------------------- 359

  Fly   538 KYRNKLTSLEPEIQNILDEEQAERQLAKTEQQLSKTERKLLGQTNERRGWFQTKQQREAEKDRLA 602
                 |.::|.||:..|.|      ||..|.|:    .::|.|.|..|        ||.| .:|.
  Rat   360 -----LHAIEEEIKQQLAE------LAVEEAQV----LQILTQVNVVR--------RECE-IKLE 400

  Fly   603 LTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEAKRN------KKKKEEPRKKTPEQ 661
            .:..||.|..           .||.:...:|:|    .||||||.      |::....::|..:.
  Rat   401 ASHFDEKKEI-----------NKRKQMILEGKD----PDLEAKRKAELAKIKQQNRRFKEKVEQT 450

  Fly   662 LAKERA 667
            |.:::|
  Rat   451 LRQQKA 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	143/427 (33%)
Ddx49	NP_001108495.2	SrmB	1..380	CDD:440279	142/420 (34%)
		Spc7	<359..>460	CDD:197874	35/160 (22%)