Protein Alignment Rs1 and ddx27

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_593214.2
• Gene: ddx27 / 2543155
• PomBaseID: SPAC30D11.03
• Length: 714
• Species: Schizosaccharomyces pombe
• Alignment Length: 744
• Identity: 293/744 - (39%)
• Similarity: 424/744 - (56%)
• Gaps: 122/744 - (16%)

  Fly     8 DLIGTI---EDDAEVENLSEDSDAEVEYQPT----KLRHKKVT-----EFEKGFEFVSSVKEYNQ 60
            |.|.||   |||...::.  |:||..|..|:    |.:.||.|     :|...|.|.:.|   |:
pombe     6 DFILTIDDSEDDIHYDDY--DADAVDEEMPSNVELKKKSKKATPAKDSDFNGEFLFEADV---NK 65

  Fly    61 D-------TWD----------------DLMKYVKRKARTKTDDKIAA------RLQKRG------ 90
            |       .||                ||...:.|. |...||:..:      .||:..
pombe    66 DLSSATDMNWDFDMGSKTESNRASNTVDLDAIISRN-RKPDDDEFPSSFPSEEELQEPEQENIDS 129

  Fly    91 ----------GAEAVAAEQSDGSEIDLSEDELKHD---------NLRLREKKESKKKKKKAGEED 136
                      ||.|: ||..|.|..|.||.|.:.|         |:..::............|||
pombe   130 DDEDLAIDGFGAGAI-AENEDESSQDESESEEEDDITEPVPSFANISTQDFNSDSAAGSSDSEED 193

  Fly   137 EEDEGEKMQ-FADTVEANEQIT----SFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRD 196
            ||:..:|.. ||:..:....:|    ||..||||||:::.:..||:..||.||..|||:||||:|
pombe   194 EEEIAKKNAFFAEGDKEKSMMTTTHSSFQSMNLSRPILKGLSNLGFEVPTQIQDKTIPLALLGKD 258

  Fly   197 ICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVG 261
            |.|.|.||:|||||:::|.|||||||| .....||||:|.|||||..|.:.|..::..||.|.|.
pombe   259 IVGAAVTGSGKTAAFIVPILERLLYRP-KKVPTTRVLILCPTRELAMQCHSVATKIASFTDIMVC 322

  Fly   262 LAIGGLDVKAQEAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMK 326
            |.||||.:|.||..||:.||||||||||.|||::|:..||:::||::::|||||||::.||:::.
pombe   323 LCIGGLSLKLQEQELRKRPDIVIATPGRFIDHMRNSQGFTVENIEIMVMDEADRMLEDGFADELN 387

  Fly   327 EIINSCCKTRQTMLFSATMSEQVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFIRIREDKEGDRE 391
            |||.:|.|:||||||||||:::|.||..:||::|::|||:|.:..|..|.|||:|:|..:|..|.
pombe   388 EIIQACPKSRQTMLFSATMTDKVDDLIRLSLNRPVRVFVDNKKTTAKLLTQEFVRVRPQRELLRP 452

  Fly   392 PILASLICRTFHDHCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDV 456
            .:|..|....||...::|.::|..||::.::.|||.:.|.|:||:|:|:||:.:|:.|::.:.:.
pombe   453 AMLIYLCKELFHRRTIIFFRSKAFAHKMRVIFGLLSLNATEIHGSLSQEQRVRALEDFRDGKCNY 517

  Fly   457 LIATDVAARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKN 521
            |:|||||:||:||.|::.|||:..|.|.|.|:|||||||||||:|.:::||||.:||::|.:.||
pombe   518 LLATDVASRGIDIKGIEVVINYEAPATHEVYLHRVGRTARAGRSGRAITLAGEGDRKVLKGVFKN 582

  Fly   522 --AEST-IKNRIIPPEIIEKYRNKLTSLEPEIQNILDEEQAERQLAKTEQQLSKTER--KLLGQT 581
              |::| :.||.:....:||:..::..|||.:|.:||||:.||:|...|:.|.|.|.  |...:.
pombe   583 SSAQNTKLVNRNLDFNKVEKFGKEIEELEPVVQKVLDEEKQERELKIAERDLKKGENIMKYGDEI 647

  Fly   582 NER--RGWFQTKQQREAEKDRLALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEA 644
            ..|  |.|||      :|||:.|      .|||..|.| |:..|||              |.:|
pombe   648 RSRPARTWFQ------SEKDKQA------SKASEAKDK-KSLAKRK--------------KQME- 684

  Fly   645 KRNKKKKEEPR--KKTP-EQLAKERAMKE 670
                 |:|.||  |||. ::|:.:::.|:
pombe   685 -----KEEVPRAYKKTKNDRLSNKKSTKK 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	210/428 (49%)
ddx27	NP_593214.2	SrmB	220..655	CDD:440279	212/435 (49%)