Protein Alignment Rs1 and hca4

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_594652.1
• Gene: hca4 / 2541630
• PomBaseID: SPAC1093.05
• Length: 735
• Species: Schizosaccharomyces pombe
• Alignment Length: 718
• Identity: 203/718 - (28%)
• Similarity: 304/718 - (42%)
• Gaps: 137/718 - (19%)

  Fly   118 RLREKKESKKKKKKAGEEDEEDEGEKMQFADTVEA-NEQITSFYQMNLSRPLMRAIGVLGYIYPT 181
            |....:|:::||:|  ||:||.|    :....:|| :|.:..|.::.|::|...|:....:|..|
pombe     5 RTGRSREAREKKRK--EEEEEIE----ELNSQIEALSETVDHFAELPLTQPTKSALKNAHFITLT 63

  Fly   182 PIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVY 246
            .||...||.||.||||.|.|.||:|||.|:::|.:|.|..:...:......||:.|||||..|.:
pombe    64 EIQKQCIPSALKGRDILGAAKTGSGKTLAFIVPLIENLYRKKWTSLDGLGALVISPTRELAIQTF 128

  Fly   247 QVTKQLCQFTTIDVGLAIGGLDVKAQ-EAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLIL 310
            :...::.:..:...||.|||.:.|.: |.:.|.|  |::.|||||:.||....:|....:::|||
pombe   129 ETLVKIGRLHSFSAGLIIGGNNYKEEKERLSRMN--ILVCTPGRLLQHIDQAVNFDTSGLQMLIL 191

  Fly   311 DEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKDLAAVSLDKP--IKVFVNNNQQVAF 373
            |||||:||..|...:..|::|....|||||||||.::.|||||.:||..|  |.|..|:......
pombe   192 DEADRILDMGFRTTLDAIVSSLPVHRQTMLFSATQTKSVKDLARLSLQNPDFISVHENDTSSTPS 256

  Fly   374 NLRQEFIRIREDKEGDREPILASLICRTFHDHCMVFVQTKKQAHRLHILLGLL--GVRAGELHGN 436
            ||.|.::.:...::.|   ||...|........:||:.:.||...::.....:  |:....|||.
pombe   257 NLNQFYLTVPLTEKLD---ILFGFIRTHLKFKTIVFLSSCKQVRFVYETFRRMRPGISLLHLHGK 318

  Fly   437 LTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAG 501
            ..|..|.|...||...:..||..||:.|||||...|..||....|...:.||||||||||..|:|
pombe   319 QKQTTRTEVTAKFTSSRHVVLFCTDIVARGLDFPAVDWVIQLDAPEDVDTYIHRVGRTARYNRSG 383

  Fly   502 ISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIEKYRNKLTSLEPEIQNILDEEQAER----- 561
            .::.|....|...:|        .::::.|..|.|.....|.||:..::||:..::...:
pombe   384 NALLLLLPSEEAFLK--------RLESKKIAVERINVKDGKKTSIRNQLQNLCFKDNDIKYIGQK 440

  Fly   562 -----------QLAKTEQQLSK------------------TERKLLGQTNERRGW---------- 587
                       |..|...||.|                  |..||...:..::.:
pombe   441 AFISYLRSIYLQKDKDVFQLDKLPVEAFADSLGLPGTPKITFGKLKNHSQSQKDYNSSTSLDSSE 505

  Fly   588 -------------------FQTKQQ--REAEKDRLALTTGDEDKA-------------------- 611
                               |:.|.|  ..|.:.||.....|||..
pombe   506 ESEVDVENKQNVRTKYDRIFERKNQDVLAAHRQRLVEVNSDEDDGDFLQVKRVDHDLPEETGERF 570

  Fly   612 -SGGKGKGKTAGKRKR---------PEYGGDGEDGPPVKDLEAKRNKKKKEEPRKKTPEQLAKER 666
             :..|.|.|.|..:|.         ..|..|..:..|...:..:...:|..:|.......||:||
pombe   571 NANSKRKEKMASSKKAMLKYKKSADKVYFDDEGNAIPFYAMNTEDTFQKAGDPAALIASHLAEER 635

  Fly   667 AMKEIEKVSL-----VRAKMAKLRKRPGKLGAATEVHRSGASDGKPKR---RGGQSAFTND-LTD 722
              |.:||..:     ||.|..:.::|      ..|:.|....|..|..   .|...||.:| |.:
pombe   636 --KALEKADITDKETVRQKQLEKKRR------RQELERITQQDATPDEYVPEGPIVAFVDDELPE 692

  Fly   723 VSR 725
            .|:
pombe   693 TSK 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	148/458 (32%)
hca4	NP_594652.1	DEADc_DDX10	50..247	CDD:350699	81/198 (41%)
		SF2_C_DEAD	258..389	CDD:350174	44/133 (33%)
		DUF4217	421..479	CDD:464056	7/57 (12%)
		COG5638	<492..717	CDD:227925	40/212 (19%)