Protein Alignment Rs1 and Ddx49

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001020093.2
• Gene: Ddx49 / 234374
• MGIID: 2136689
• Length: 480
• Species: Mus musculus
• Alignment Length: 533
• Identity: 168/533 - (31%)
• Similarity: 263/533 - (49%)
• Gaps: 86/533 - (16%)

  Fly   156 ITSFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLL 220
            :..|.::.||..|:.....||...|||:|...||..|.|||..|||.||:|||||::||.|::|.
Mouse     1 MAGFAEIGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLS 65

  Fly   221 YRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIA 285
            ..|..    ...|||.|||||..|:.:..:.|.:...:...:.:||:|:.||...|.:.|.:|||
Mouse    66 EDPYG----IFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIA 126

  Fly   286 TPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDE---YFAEQMKEIINSCCKTRQTMLFSATMSE 347
            |||||.||::::.:|.:..|:.|::|||||:|::   .|...::.|:.:....|||:|||||:::
Mouse   127 TPGRLADHLRSSNTFNMKKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPARRQTLLFSATLTD 191

  Fly   348 QVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFIRIREDKEGDREPILASLICRTFHDH---C--M 407
            .:|:|..::.::|.........:....|.|.::.:.|..   ::..|..|: :||.|.   |  :
Mouse   192 TLKELQGLATNEPFFWEAQATVRTVEQLDQRYLLVPEKV---KDAYLVHLV-QTFQDQLEDCSII 252

  Fly   408 VFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGV 472
            :|..|.|....|.::|.........||..:.|::|..:|.|||.....:|||||||:|||||..|
Mouse   253 IFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317

  Fly   473 KTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIE 537
            :.|||...|...:.|||||||||||||.|.:::|..:.:..::..|
Mouse   318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLLHAI------------------- 363

  Fly   538 KYRNKLTSLEPEIQNILDEEQAERQLAKTEQQLSKTE-RKLLGQTNERRGWFQTKQQREAEKDRL 601
                              |||.::|||  |..:.:.| .::|.|.|..|        ||.| .:|
Mouse   364 ------------------EEQIKQQLA--ELVVEEAEVLQILTQVNVVR--------RECE-IKL 399

  Fly   602 ALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEAKRN------KKKKEEPRKKTPE 660
            ..:..||.|..           .||.:...:|:|    .||||||.      |::....::|..:
Mouse   400 EASHFDEKKEI-----------NKRKQMILEGKD----PDLEAKRKAELAKIKQQNRRFKEKVGQ 449

  Fly   661 QLAKERAMKEIEK 673
            .|.:::|...:.:
Mouse   450 TLRRQKAGSTVRR 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	143/428 (33%)
Ddx49	NP_001020093.2	SrmB	1..380	CDD:440279	142/425 (33%)
		Q motif	2..30		9/27 (33%)
		DEAD box	152..155		2/2 (100%)
		PRK03918	<364..>447	CDD:235175	30/108 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	438..480		3/25 (12%)