Protein Alignment Rs1 and ddx-27

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_490891.2
• Gene: ddx-27 / 171743
• WormBaseID: WBGene00022148
• Length: 739
• Species: Caenorhabditis elegans
• Alignment Length: 802
• Identity: 334/802 - (41%)
• Similarity: 470/802 - (58%)
• Gaps: 108/802 - (13%)

  Fly    22 LSEDSDAEVEYQPTKLRHKK-----VTEFEKGFEFVSSVKEYNQDTWDDLMKYVKRKARTKTDDK 81
            :.|..|.:|:.:...:|.||     ..||.:.|.|.|...::.....:||.||:|::..|..|:|
 Worm     3 IDESDDEQVQDEAVTVRKKKKMANAAEEFAQDFIFESGDTQFIDRETEDLQKYLKKQTPTSLDEK 67

  Fly    82 IA--ARLQKRGGAEAV--AAEQSDGSEIDLSEDELKHDNLRLREKKESKKKKKKAGEEDEEDEGE 142
            ||  .:|:..|.|..|  .||.::..|.|..||:::  .|..:|.:::.::|:|:|:..:..|.|
 Worm    68 IAEMRKLKNTGKAVIVEDEAEAAEAEEKDEEEDDVQ--QLGGKETRDTVREKRKSGKSKKSQENE 130

  Fly   143 KMQFADTVEANEQIT----SFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAAT 203
            .. |:..::.....|    ||.||||||.:::|....||..|||||.:.|||||.|:|||.||||
 Worm   131 DF-FSALIDGKSLDTSVNVSFEQMNLSRQILKACSGAGYSDPTPIQQACIPVALTGKDICACAAT 194

  Fly   204 GTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLD 268
            |||||||::||.|||::||| ...:.||||||||||||..||:||.::|..|..::|.|..||||
 Worm   195 GTGKTAAFVLPILERMIYRP-KGASCTRVLVLVPTRELAIQVFQVFRKLSTFIQLEVCLCAGGLD 258

  Fly   269 VKAQEAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCC 333
            :|||||.||..||:|:|||||||||:.|:|||.|.:||||:||||||||:|.|.:||.|:|..|.
 Worm   259 LKAQEAALRSGPDVVVATPGRLIDHLHNSPSFNLSNIEVLVLDEADRMLEEAFRDQMNELIRLCA 323

  Fly   334 KTRQTMLFSATMSEQVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFIRIREDKEGDREPILASLI 398
            :.|||:||||||:|::.:||::||.||:|:|:|.|...|..|||||||||..:|.|||.::|:|:
 Worm   324 QNRQTLLFSATMTEEIDELASMSLQKPVKIFINENTDTALKLRQEFIRIRAGRETDREAMVAALV 388

  Fly   399 CRTFHDHCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVA 463
            .|||..:.:|||:|||...|:.|||||||::.|::..:|||.||:|||.|||:.:||||::||:|
 Worm   389 TRTFQTNTIVFVRTKKDCQRMQILLGLLGIKVGQMQSSLTQGQRIESLSKFKKAEIDVLVSTDLA 453

  Fly   464 ARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDII-KNAESTIK 527
            :|||||.||:||||..||.:.:.||||||||||||:||.|:||.||.|||::|:|: .||:.|:|
 Worm   454 SRGLDIEGVQTVINMNMPKSIKQYIHRVGRTARAGKAGRSISLVGEDERKLLKEIVNSNADRTLK 518

  Fly   528 NRIIPPEIIEKYRNKLTSLEPEIQNILDEEQAERQLAKTEQQLSKTERKL-LGQTN----ERRGW 587
            .|::.||::|.||.::..||..||.|.:|::||::|...|..::||:..| :|:..    |||.|
 Worm   519 QRLVAPEVVEAYRRRIDELEETIQQIDEEDRAEKELRIAEASMAKTQNALEVGENGGAPAERRVW 583

  Fly   588 FQTKQQREAEKDRLALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEAKRNKK--- 649
            ...:.|.|.::.|                                          |.||..|
 Worm   584 MMKESQIEKQRKR------------------------------------------EEKRQMKVDA 606

  Fly   650 KKEEPRKKTPEQLAKERAMKEIEKVSLVRAKMAKLRKRPGKLGAATEVHRSGASDGKPK----RR 710
            :|:....||||.:       :||..:....:.|| |.|..|......|..|..:.|..|    ::
 Worm   607 RKKAEAAKTPEDI-------QIEHEAAFHVRAAK-RARHSKNKRIRAVVESAGTKGAGKAAQNKK 663

  Fly   711 GGQSAFTNDLTDV------SRGGALRLRSEANRHKKMTKIAAKK-----KASSVKLTNKAGK--- 761
            ...|.....|.|:      |||        ..:.:|..|..|||     .||..|.:.||.:
 Worm   664 KASSNSKTSLRDIPLVNAGSRG--------VQKAQKGQKPGAKKGFTSALASVSKKSVKAARHGP 720

  Fly   762 --NKFNKGKNFGGPRHAKKDKK 781
              :||.|.:    ..|..|.||
 Worm   721 EDSKFQKAR----VAHRMKTKK 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	243/424 (57%)
ddx-27	NP_490891.2	SrmB	149..567	CDD:440279	242/418 (58%)
		valS	<486..716	CDD:237855	81/287 (28%)