Protein Alignment trbl and trib3

DIOPT Version :10

• Sequence 1: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_998034.1
• Gene: trib3 / 405805
• ZFINID: ZDB-GENE-040426-2609
• Length: 348
• Species: Danio rerio
• Alignment Length: 284
• Identity: 108/284 - (38%)
• Similarity: 159/284 - (55%)
• Gaps: 38/284 - (13%)

  Fly   126 PASYRH---------LVDLT--ASNLRCVDIFTGEQFLCRIVNEPLHKVQRAYFQLQQHDEELRR 179
            |.|.:|         |::.|  |...|.|...|.:::.|::            |.::::.|.:..
Zfish    57 PGSEKHHVSRIGPYILLEATEVAQTFRAVHQVTEQEYTCKV------------FSMKKYHEFIAP 109

  Fly   180 ST-IYGHPLIRPVHDIIPLTKDRTYILIAPVPQERDSTGGVTGVYENLHTYIRHAKRLCETEARA 243
            .| :..|..|..:.::: |.::..||..     ||:        |.::|:|:|..|||.|.||..
Zfish   110 YTRLLPHSNICKISEVV-LGENNVYIFF-----ERN--------YGDMHSYVRTCKRLQEDEAVR 160

  Fly   244 IFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGSMILDGEDDTLSDKIGCPLYT 308
            :|.|:...|..||.||:|||||||::|.|.|:.||||..::||.|.:|:|.||:|:||.|||.|.
Zfish   161 LFTQMASAVAHCHENGVILRDLKLRKFVFTDQQRTKLVLQNLEDSCLLNGNDDSLTDKHGCPAYV 225

  Fly   309 APELLCPQQTYKGKPADMWSLGVILYTMLVGQYPFYEKANCNLITVIRHGNVQIPLTLSKSVRWL 373
            .||:|..:.:|.||.||:|||||:|||||||:|||.:.....|.:.||.|...:|.|||...:.|
Zfish   226 GPEILNSRHSYSGKAADIWSLGVVLYTMLVGRYPFQDVEPTALFSKIRRGAFTVPETLSPRAKSL 290

  Fly   374 LLSLLRKDYTERMTASHIFLTPWL 397
            :..:|||..:||:.|..|.|.|||
Zfish   291 VYCMLRKCPSERLEAGDILLHPWL 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trbl	NP_524672.1	Protein Kinases, catalytic domain	131..397	CDD:473864	104/277 (38%)
trib3	NP_998034.1	PK_TRB3	73..314	CDD:270926	102/266 (38%)