Protein Alignment trbl and trib2

DIOPT Version :10

• Sequence 1: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: XP_012818292.1
• Gene: trib2 / 394677
• XenbaseID: XB-GENE-489426
• Length: 343
• Species: Xenopus tropicalis
• Alignment Length: 302
• Identity: 109/302 - (36%)
• Similarity: 169/302 - (55%)
• Gaps: 42/302 - (13%)

  Fly   111 SAQPS-----HISAAVAAKTPAS---------YRHLVDLTASNL-RCVDIFTGEQFLCRIVNEPL 160
            |.:||     ::.:....:||.|         |..|..|..::: |.:.:.:||:|||::
 Frog    32 STEPSQSFSPNLGSPSPPETPNSSHCVSCIGKYLLLEPLEGNHVFRALHLHSGEEFLCKV----- 91

  Fly   161 HKVQRAYFQLQQHDEELRRS-TIYGHPLIRPVHDIIPLTKDRTYILIAPVPQERDSTGGVTGVYE 224
                   |.::.:.|.|... .:..|..|..:.:|| |.:.:.|:..     ||.        :.
 Frog    92 -------FDIRCYQETLAPCFCLPIHSNINQIAEII-LGETKAYVFF-----ERS--------HG 135

  Fly   225 NLHTYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGSM 289
            ::|:::|..|:|.|.:|..:|:||...|..||..||:||||||::|.|.|..|||::.|:||.:.
 Frog   136 DMHSFVRTCKKLKEEDAARLFYQIVSAVAHCHDGGIVLRDLKLRKFVFNDGERTKVKLETLEDAY 200

  Fly   290 ILDGEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTMLVGQYPFYEKANCNLITV 354
            :|.|.||:||||.|||.|.:||:|....:|.||.||:|||||:|||||||:|||::....:|.:.
 Frog   201 VLAGTDDSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265

  Fly   355 IRHGNVQIPLTLSKSVRWLLLSLLRKDYTERMTASHIFLTPW 396
            ||.|...||.|||...:.|:.|:||::.:||:|:..|...||
 Frog   266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPW 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trbl	NP_524672.1	Protein Kinases, catalytic domain	131..397	CDD:473864	102/268 (38%)
trib2	XP_012818292.1	PK_TRB2	67..308	CDD:270924	102/267 (38%)