Protein Alignment trbl and Trib2

DIOPT Version :10

• Sequence 1: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001101485.2
• Gene: Trib2 / 313974
• RGDID: 1564451
• Length: 343
• Species: Rattus norvegicus
• Alignment Length: 350
• Identity: 121/350 - (34%)
• Similarity: 182/350 - (52%)
• Gaps: 61/350 - (17%)

  Fly   111 SAQPS-----HISAAVAAKTPASYRHLVDLTASNL-----------RCVDIFTGEQFLCRIVNEP 159
            ||:||     ::.:....:|| :..|.|......|           |.|.:.:||:.:|::
  Rat    32 SAEPSQSFSPNLGSPSPPETP-NLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKV---- 91

  Fly   160 LHKVQRAYFQLQQHDEELRRS-TIYGHPLIRPVHDIIPLTKDRTYILIAPVPQERDSTGGVTGVY 223
                    |::..:.|.|... .:..|..|..:.:|: |.:.:.|:..     ||.        |
  Rat    92 --------FEISCYQESLAPCFCLSAHSNINQITEIL-LGETKAYVFF-----ERS--------Y 134

  Fly   224 ENLHTYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGS 288
            .::|:::|..|:|.|.||..:|:||...|..||..|::||||||::|.|.||.||:::.||||.:
  Rat   135 GDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDA 199

  Fly   289 MILDGEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTMLVGQYPFYEKANCNLIT 353
            .||.|:||:||||.|||.|.:||:|....:|.||.||:|||||:|||||||:|||::....:|.:
  Rat   200 YILRGDDDSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFS 264

  Fly   354 VIRHGNVQIPLTLSKSVRWLLLSLLRKDYTERMTASHIFLTPWLREQRPFHMYLPVDVEVAEDWS 418
            .||.|...||.|||...:.|:.|:||::.:||:|:..|...||          ...|..|:....
  Rat   265 KIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPW----------FSTDFSVSNSGF 319

  Fly   419 DAEEDEGTAADAMDDD---EEGLCP 440
            .|:|    |.|.:..|   ||.|.|
  Rat   320 GAKE----ACDQLVPDVNMEENLDP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trbl	NP_524672.1	Protein Kinases, catalytic domain	131..397	CDD:473864	103/277 (37%)
Trib2	NP_001101485.2	PK_TRB2	67..308	CDD:270924	101/276 (37%)