Protein Alignment Pten and PEN3

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_566929.1
• Gene: PEN3 / 824173
• AraportID: AT3G50110
• Length: 632
• Species: Arabidopsis thaliana
• Alignment Length: 550
• Identity: 162/550 - (29%)
• Similarity: 244/550 - (44%)
• Gaps: 137/550 - (24%)

  Fly     5 ISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPD-------KLEGLFRNRLEDVF 62
            :..|....|::||:.:.||:|..:|||:|||.:||||||:||.|       ..|||:||.:|:|.
plant   173 VKAMQVKARHIVSQNKRRYQEGEFDLDMTYITENIIAMGFPAGDISSGLFGFFEGLYRNHMEEVI 237

  Fly    63 KLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNV 127
            |..|.:|...||:|||||||.||.::|.|:||.:||||||.|.|:||..||.....|||||..||
plant   238 KFFETHHKDKYKVYNLCSERLYDASRFEGKVASFPFDDHNCPPIQLIPSFCQSAYTWLKEDIQNV 302

  Fly   128 VAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKL--- 189
            |.||||||..|||.|||..|::.....:|:||:.:|::||..|.|.:.:|||.|||:|:.::
plant   303 VVVHCKAGMARTGLMICCLLLYLKFFPTAEEAIDYYNQKRCLDGKALVLPSQIRYVKYYERVQNQ 367

  Fly   190 VCSSVPYSKVSLNVCEIRFSESSC-VQNLGMVEC--------SISVLHDSATENAKPDRLKTL-P 244
            ....||             .|..| ::...::.|        :||...|......|..:.|.| |
plant   368 FDGKVP-------------PERRCMLRGFRLINCPYWIRPAITISNHTDILFSTKKHQKTKDLGP 419

  Fly   245 IDF-----QKSFVLTIKPS----IPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTV 300
            .||     :|..|:...|.    ..::||.|........| ..|  ||||....|.:
plant   420 EDFWIKAPKKGVVVFAIPGEAGLTELAGDFKIHFQDSDGD-FYC--WLNTTLTDNRT-------- 473

  Fly   301 NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF---------EAENFSNDVQAEASEKERNENV 356
                 .|..|:.|...|   .|..:..|.:.||.         ::::.|...|:::|....:..:
plant   474 -----MLKGSDFDGFDK---RKLPAPGFHVEIVMIEPDNSQPTKSKSDSTQQQSQSSSSADSSKL 530

  Fly   357 LNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKR 421
            .:.|:.|                                   |:.:....:...||::.||
plant   531 KSNEKDD-----------------------------------DVFSDSDGEEEGNSQSYST---- 556

  Fly   422 KQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTD-----LIKWQNSEVH---ITSDTRSINENK 478
               |.||.      |:.....:.|..|:|. |:.|     .:...:|..|   |.:::.::::.|
plant   557 ---NEKTA------SSMHTTSKPHQINEPP-KRDDPSANRSVTSSSSSGHYNPIPNNSLAVSDIK 611

  Fly   479 NINYNSYITCKQSSPKFNCGTEDGEEDWES 508
            .|..::.:        |:.|  |.|||:||
plant   612 AIAADASV--------FSFG--DEEEDYES 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	86/164 (52%)
		PTEN_C2	196..335	CDD:463081	33/166 (20%)
PEN3	NP_566929.1	PTP_PTEN	199..363	CDD:350359	86/163 (53%)