Protein Alignment Pten and tns2a

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_021325579.2
• Gene: tns2a / 799109
• ZFINID: ZDB-GENE-090312-163
• Length: 1616
• Species: Danio rerio
• Alignment Length: 471
• Identity: 119/471 - (25%)
• Similarity: 200/471 - (42%)
• Gaps: 97/471 - (20%)

  Fly     1 MANTISLMSNVIRNVV----SKKRI--RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLE 59
            :.:|.||.....||.:    |..|:  |..|:.||.|||||.:.||::.:| |...|..:|..|.
Zfish   112 LGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFP-PLLEEQRYRLNLR 175

  Fly    60 DVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDS 124
            :|..:|:..|...:.:.|| |||.:|:.:...:|..:.:.|.:.|.::.|...|..::.||..|.
Zfish   176 EVAAMLKSKHQDKFLLLNL-SERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDP 239

  Fly   125 SNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYD-EKRTKDRKGVTI-PSQRRYVQYFS 187
            .:||.:|||..||:||.:|.||:.:|.|...||:||:... .|..:|:...:: |||.||:|||.
Zfish   240 QHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFG 304

  Fly   188 KLVCSSVPYSKVSLNVCEI------RFSES-------SCVQNLGMVECS-ISVLHDSATENAKPD 238
            .|:..|:..:...|.:.::      .|.|.       ...|::.:|..| |..|..||:
Zfish   305 GLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSAS------ 363

  Fly   239 RLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKY 303
                      :..::||:|::.:.||:          .:.|:.       |.....|.|......
Zfish   364 ----------RRLIITIEPALLLKGDI----------MVKCYH-------RRVESAERDSVFRLQ 401

  Fly   304 IHT---------LSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNF 359
            .||         ..|.|:|:...|.   :|..:..:..||.    |...:.:....:||:..::.
Zfish   402 FHTCTVHAAQLWFGKGELDEACSDD---KFPPDAIVEFVFS----SGPEKIKGRVSQRNDPAVSV 459

  Fly   360 ERSDYDSLSP----NCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACK 420
               ||::..|    :.|.         |.|.....::|.:.|    |:...|.|..::    ..|
Zfish   460 ---DYNTNDPVVRWDSYE---------NFNQRHQDSLEDIAH----TRGPVDGSLYAQ----VKK 504

  Fly   421 RKQPNSKTLLPSLNDS 436
            |:.....:.|||.|.|
Zfish   505 RRAAAGCSSLPSTNGS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	57/159 (36%)
		PTEN_C2	196..335	CDD:463081	27/161 (17%)
tns2a	XP_021325579.2	None