Protein Alignment Pten and Dnajc6

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001158055.1
• Gene: Dnajc6 / 72685
• MGIID: 1919935
• Length: 968
• Species: Mus musculus
• Alignment Length: 521
• Identity: 115/521 - (22%)
• Similarity: 210/521 - (40%)
• Gaps: 127/521 - (24%)

  Fly     9 SNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHY 73
            |.||::|.|      ..|| |||.||:...||.|.:|. |.::..|||:::|:...|:..|..||
Mouse   105 SRVIQSVSS------YTKG-DLDFTYVTSRIIVMSFPV-DSVDIGFRNQVDDIRSFLDSRHLDHY 161

  Fly    74 KIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGR 138
            .:||| |.:||..|||..||:...:.....|::..:...|.::..||.::..||..|||..|:..
Mouse   162 TVYNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAA 225

  Fly   139 TGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI-PSQRRYVQYFSKLVC----------- 191
            :..::.|..:|..:..:...|:.....|    |.|:.: ||.|||:.|...|:.
Mouse   226 SSILVGAMFIFCNLYSTPGPAVRLLYAK----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPL 286

  Fly   192 -------SSVPYSKVSLN----VCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPI 245
                   |.||:.....|    .|::...|:.              ::.:.|:.   :|:|...:
Mouse   287 TIKAITVSPVPFFNKQRNGCRPYCDVLIGETK--------------IYSTCTDF---ERMKEYRV 334

  Fly   246 DFQKSFV---LTIKPSIPVS-----GDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNK 302
            ...|.|:   :|::..:.||     ..:...|..|..:..|.....::.|:      ..|.||.|
Mouse   335 QDGKIFIPLNITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFI------PLDTTVLK 393

  Fly   303 YIHTLSKSEID--DVHKDSEHKRFSEEFKISIVFEA-------------ENF-SNDVQAE---AS 348
            :    :|.|:|  ||     .:::.:.|::::..|.             |:: :.||...   :|
Mouse   394 F----TKPELDACDV-----PEKYPQLFQVTLDIEVQPQDKVIDLTPPWEHYCTKDVNPSILFSS 449

  Fly   349 EKERNENVLNFERSDYDSLSPN--------------CYAEKKVLTAIVNDNTTKSQTIETLDHKD 399
            ::|..:.:....::..| |.|:              |:.::|         :.||:..|  ||..
Mouse   450 QQEHQDTLALGGQAPAD-LPPDHPRNLGQGGFFASLCWQDQK---------SEKSRCEE--DHAA 502

  Fly   400 IVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSE 464
            :|.:    .|..|.:..........|::...|  :.:.|...|:......|..::.||:..:.|:
Mouse   503 LVNQ----ESEQSDDELLTLSSPHGNAEGDKP--HGAKKPGKKQQEPAAPPPPEEVDLLGLEGSD 561

  Fly   465 V 465
            |
Mouse   562 V 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	49/158 (31%)
		PTEN_C2	196..335	CDD:463081	25/152 (16%)
Dnajc6	NP_001158055.1	PTP_auxilin_N	111..273	CDD:350411	55/174 (32%)
		PTEN_C2	281..419	CDD:463081	28/169 (17%)
		PPE	<562..782	CDD:444372	1/1 (100%)
		DnaJ	<916..961	CDD:99751