Protein Alignment Pten and Tpte2

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001406113.1
• Gene: Tpte2 / 364629
• RGDID: 1305825
• Length: 674
• Species: Rattus norvegicus
• Alignment Length: 359
• Identity: 122/359 - (33%)
• Similarity: 185/359 - (51%)
• Gaps: 62/359 - (17%)

  Fly     8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQH 72
            :..:.|.:||..:.|||:.|:||||||:.:.||||.:|:..: |..:||.:::|.:.|:..|..|
  Rat   339 LEKLTRQLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGR-ESFYRNPIKEVVRFLDTKHPNH 402

  Fly    73 YKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKG 137
            |::||||||||||..:|..||.....||||.||:|.:..|..:|:.|:.:|..||||:|||.|||
  Rat   403 YQVYNLCSERSYDPKRFHYRVRRIMIDDHNVPTLEEMLLFSKEVNDWMAQDPENVVAIHCKGGKG 467

  Fly   138 RTGTMICAYLVFSGIKKSADEALAWYDEKRTKDR------KGVTIPSQRRYVQYFSKLVCS---S 193
            |||||:||.|:.|.|..:|..:|.::.|:|| |:      :||..|||.|||:||.||..|   :
  Rat   468 RTGTMVCACLIASEIVLNAKASLYFFGERRT-DKSNSSKFQGVETPSQNRYVKYFEKLKTSYQLT 531

  Fly   194 VPYSKV--------------------SLNVCEIRFSES--SCVQNLGMVECSISVLHDSATENAK 236
            :|..||                    .|.:..:.:.|:  ||..:...:     :.||..|:...
  Rat   532 LPPKKVLVIKRFTVYSIHGVGKGNGSDLEIQIMMWQETIFSCFNSKNCM-----IFHDVETDKVI 591

  Fly   237 PDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVN 301
            .: :...|..:....|..:.|::|           |..|.....||.:|.|:||          |
  Rat   592 IN-VFNCPALYDDVKVKFLCPNLP-----------KYYDDCPFFFWFHTSFIRN----------N 634

  Fly   302 KYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFE 335
            :..  |.:||:|:.||....|.:..:|.:.:.||
  Rat   635 RLY--LPRSELDNTHKQKTWKIYGPKFAVEVYFE 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	77/163 (47%)
		PTEN_C2	196..335	CDD:463081	30/160 (19%)
Tpte2	NP_001406113.1	PTP_VSP_TPTE	348..524	CDD:350360	84/177 (47%)
		PTEN_C2	533..667	CDD:463081	33/163 (20%)