Protein Alignment Pten and ptn1

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_596312.1
• Gene: ptn1 / 2541101
• PomBaseID: SPBC609.02
• Length: 348
• Species: Schizosaccharomyces pombe
• Alignment Length: 362
• Identity: 113/362 - (31%)
• Similarity: 168/362 - (46%)
• Gaps: 54/362 - (14%)

  Fly    10 NVIRNVVSKKRIRYKEKGYD-----LDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENH 69
            |::|:|||:.|...|::..:     ||:.||...:|||..||.. :..|:||...||||.|....
pombe     2 NILRSVVSRGRKGLKQEKVNRSFAYLDMVYITSKVIAMSTPAAG-IHKLYRNDELDVFKYLTTQL 65

  Fly    70 AQHYKIYNLCSERS-YDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCK 133
            ..::.:.|||:|.: |.:..|:..|..|.|.|||||.:..:.....::|...:......:.||||
pombe    66 KDNWILLNLCAEETVYHLELFKPNVINYGFQDHNPPPLLFLWAIVMNMDALFQTQPLLTLVVHCK 130

  Fly   134 AGKGRTGTMICAYLV-FSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVP-Y 196
            ||||||||:||:||| |.|:  :|.::|..|.|||.....|:||.||.|||.|..  :....| |
pombe   131 AGKGRTGTVICSYLVAFGGL--TAKQSLELYTEKRMVRGHGLTISSQIRYVYYIE--ILKQFPNY 191

  Fly   197 SK-VSLNVCEIRFSESSCVQNLGMVECSISVLHD-SATENAKPDRL-KTLPIDFQKSFVLTIKPS 258
            .| |..|.....|....|: |:......|..||. |...|..|..| |:..|   .|..::||..
pombe   192 LKAVEFNTGTTFFKSFKCL-NIKKNSSLILSLHAFSKGRNINPVALWKSSDI---SSHNVSIKEG 252

  Fly   259 IPVSG----------DVKFELTKKS----PDKIICHFWLNTFF----VRNYSPCESDGTVNKYIH 305
            ..:.|          |:...:.:|.    |..:.|  |.:|.|    |...:.......:|.::.
pombe   253 KRIWGIQCNLETSEKDLLLRVERKGQFYFPSSVQC--WFHTHFQPMLVEYTNGINFQQGINSFLQ 315

  Fly   306 -----TLSKSEIDDVHKDSEHKRFSEEF--KISIVFE 335
                 :.|.||:|       :.|.|:.|  :::||:|
pombe   316 GQQSISFSWSEMD-------NSRRSDPFFEQLTIVYE 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	65/159 (41%)
		PTEN_C2	196..335	CDD:463081	38/166 (23%)
ptn1	NP_596312.1	PTP_PTEN-like	28..185	CDD:350347	65/161 (40%)