DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pten and by

DIOPT Version :10

Sequence 1:NP_477422.2 Gene:Pten / 43991 FlyBaseID:FBgn0026379 Length:514 Species:Drosophila melanogaster
Sequence 2:XP_061499716.1 Gene:by / 1281495 VectorBaseID:AGAMI1_006423 Length:2450 Species:Anopheles gambiae


Alignment Length:499 Identity:96/499 - (19%)
Similarity:169/499 - (33%) Gaps:161/499 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 RIRYKEKGYDLDLTYINDNIIAM------------------GYPAPDKLEGLFRNRLEDVFKLLE 66
            ||..:.....|.|.|:.:.|:|.                  |.|..|:.|       .::..:||
Mosquito   448 RIDEEPAAQSLRLNYVTERILASTLPARRLQNGSSSPHTPNGTPPVDEHE-------RELINMLE 505

  Fly    67 ENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVH 131
            :.|.|:|:|.:| ..|..::                  |:|.:...|..:|.||......:|.:.
Mosquito   506 QKHKQNYRILDL-EARLVNI------------------TLEKLCELCKYIDSWLGSGKEKIVVLQ 551

  Fly   132 CKAGKGRTGTMICAYLVF-----------SGIKKSA---------DEALAWYD------EKRTKD 170
            .:..|.|.||.|.|||.:           ||..|::         .....|.|      :|..:.
Mosquito   552 DREDKHRLGTAIAAYLQYQKICGSNIPQASGHSKNSLSPGGTDNGRRTPTWLDLDIYSMQKFLET 616

  Fly   171 RKG-VTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSA-TE 233
            ..| :.|||.|||:||||.|:...:..:..|..:..||.....|             ||..| |.
Mosquito   617 VAGPLRIPSHRRYIQYFSGLLSGVIKLNSSSFFLKAIRVESPPC-------------LHYRAITV 668

  Fly   234 NAK---------------PDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWL 283
            |::               ...:..:||. .:.|:..||..:.:.||:.....:..|:        
Mosquito   669 NSEWRSFIKIFEGVRCLFTSDIYVIPIT-TRHFIYEIKHPLRLRGDILVRCYQIIPN-------- 724

  Fly   284 NTFFVRNYSPCESDGTVNKYIHT--LSKSEID----DVHKDSEHKRFSEEFKISIVFEAENFSND 342
                 .|.:..|.:...:...||  :::.|:.    ||....|.:|||.|.:::..|:.      
Mosquito   725 -----NNKATYEKELIASVQFHTCAITEKEVQFTKGDVDFACEDERFSAEHRMTFCFDT------ 778

  Fly   343 VQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYD 407
                                     .||    ::.:..:..|...:.:.|  .::.|::..|...
Mosquito   779 -------------------------VPN----ERPMILVFQDPLVRIEPI--AENGDLLETINEG 812

  Fly   408 TSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPS 451
            .|...::..|    :.|...:|..::..|.|......|:.:.|:
Mosquito   813 WSKKDESGHT----QGPLDGSLYATILKSPKSPTATTHLISPPA 852

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PtenNP_477422.2 PTP_PTEN 31..189 CDD:350359 48/202 (24%)
PTEN_C2 196..335 CDD:463081 29/160 (18%)
byXP_061499716.1 None

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