Protein Alignment Pten and pten

DIOPT Version :10

• Sequence 1: NP_477422.2
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001116943.1
• Gene: pten / 100144716
• XenbaseID: XB-GENE-491433
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 435
• Identity: 173/435 - (39%)
• Similarity: 240/435 - (55%)
• Gaps: 71/435 - (16%)

  Fly     8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQH 72
            |:.:|:..||:.:.||:|.|:|||||||..||||||:|| ::|||::||.::||.:.|:..|..|
 Frog     1 MTAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPA-ERLEGVYRNNIDDVVRFLDSKHKNH 64

  Fly    73 YKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKG 137
            |||||||:||.||..||..|||.|||:|||||.:|||:.||.|:|.||.| :.||.|:|||||||
 Frog    65 YKIYNLCAERHYDTNKFSCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSE-NENVAAIHCKAGKG 128

  Fly   138 RTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLN 202
            |||.||||||:..|....|.|||.:|.|.||:|:||||||||||||.|:|.|:.:::.|..|.|.
 Frog   129 RTGVMICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNNLEYRPVPLL 193

  Fly   203 VCEIR------FSESSCVQNLGMVECSISVLHDSATENAKPDRL-KTLPIDFQKSFVLTIKPSIP 260
            ..:|.      ||.|:|.....:.:..:.:.    |..|.|.|: |.:..||.:        .:|
 Frog   194 FHKIEFETIPMFSGSTCNPQFVVYQLKVKIF----TSTAGPKRIEKLMYFDFPQ--------PLP 246

  Fly   261 VSGDVKFELTKKSPDKI-----ICHFWLNTFFV---RNYSPCESDGTV----------------- 300
            |.||:|.|...|. :|:     :.|||:||||:   ..||....:||:
 Frog   247 VCGDIKVEFFHKQ-NKVMKKEKMFHFWINTFFIPGPEEYSEKVENGTLVGEQELDGIYSTERSDN 310

  Fly   301 -NKYIH-TLSKSEIDDVHKDSEHKRFSEEFKISIVF--EAENFSNDVQAEASEKERNENVLNFER 361
             .:|:. ||:|:::|..:||..::.||..||:.:.|  ..|..||      ||...:.:|    .
 Frog   311 DKEYLTLTLTKNDLDKANKDKANRLFSPNFKVKLFFTKTVEESSN------SEASSSTSV----T 365

  Fly   362 SDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDI--VTKI 404
            .|.....|:.|.        .:|.|......|..|...|  :||:
 Frog   366 PDVSDNEPDHYR--------YSDTTDSDPENEPFDEDQITQITKV 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_477422.2	PTP_PTEN	31..189	CDD:350359	100/157 (64%)
		PTEN_C2	196..335	CDD:463081	46/174 (26%)
pten	NP_001116943.1	PTP_PTEN	24..180	CDD:350359	100/157 (64%)
		PTEN_C2	187..348	CDD:463081	46/173 (27%)