Protein Alignment Plap and Plap

DIOPT Version :10

• Sequence 1: NP_524666.2
• Gene: Plap / 43978
• FlyBaseID: FBgn0024314
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_314716.5
• Gene: Plap / 1275469
• VectorBaseID: AGAMI1_001898
• Length: 820
• Species: Anopheles gambiae
• Alignment Length: 836
• Identity: 372/836 - (44%)
• Similarity: 504/836 - (60%)
• Gaps: 81/836 - (9%)

  Fly     5 LDNYKLSCELLGHSMDVRAVAVGPPTPEGRQTILSGSRDKSTKVWKPHGNEYLESL-TLQDHKNF 68
            ::::||||||:||.:|||||.      ||...|:||||||:.|||:..||...|.: ||..|.|:
Mosquito     4 IEDFKLSCELVGHKLDVRAVT------EGAGFIVSGSRDKTAKVWQAVGNNRYEDVQTLTSHTNY 62

  Fly    69 ISYICFLESERWICTASNDATICIYKQDGFV--------PLLTLKGHESTVCALSAGLEPRSLIS 125
            :..:..:||..|:||.||||||||::..|.:        |:..||||.||||||:.|....:|||
Mosquito    63 VGAVLVVESNGWVCTGSNDATICIFQYPGGLGSGTANAEPIGVLKGHTSTVCALAEGHNATTLIS 127

  Fly   126 GSWDKTARVWTISEAGDVSFVALEGHEAAVWAVATLKEQRKYVTGGADRNIYYWNAKGEKLRLLK 190
            |||||||::|| :..|..:.:.|.||||||||||.|...| |::|.||:||:.||.:||||.:||
Mosquito   128 GSWDKTAKIWT-NAPGSNTNLTLVGHEAAVWAVACLPSGR-YLSGSADKNIFVWNERGEKLAVLK 190

  Fly   191 GHTDCVRGVMGLDANTLLSCGNDAVLRFWNEDGECVREMNGHSNYIYSMARNEALGDQVVVSCGE 255
            ||.|||||:..|.....|||.|||.:|:|::..|||:|.:||||||||:.|::|.|::|.|:.||
Mosquito   191 GHKDCVRGLCPLPKGGFLSCSNDATVRYWSDTYECVKEFHGHSNYIYSIGRSDAWGEEVFVTGGE 255

  Fly   256 DSTLRMWNVITGDELGAPIIHPGISVWSVTCLQNGDIVTGCSDGVVRVFSHVPARQASEAVLKAF 320
            |||:|||::..| .||..:..|..|||:|..|:|||:|.|.||.:||||:....|.|||..|.|:
Mosquito   256 DSTIRMWHLRDG-ALGDALQMPAQSVWAVAGLRNGDMVAGTSDAIVRVFTMSAERAASEEALAAY 319

  Fly   321 DLVVATRKSQINEEIGGVKKTDLPGPEALLSNGTREGQTKMVRHADGSVKCYTWTLGNWNLVGDV 385
            .:.|..|:|:..:::||:...||||||:|||.| |:|||::|||.:|.:.||.||.|.|:.||||
Mosquito   320 RVAVEVRQSESAKQLGGMNVNDLPGPESLLSEG-RDGQTRIVRHPNGKILCYQWTNGKWDCVGDV 383

  Fly   386 TGATGGTQSNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDDPWQAAQTFIHRHSLPQAYLD 450
            .||:.|   :.||:|:||:|||:||||::||..|.:||||||.:|||..||.|||:|:|||||||
Mosquito   384 MGASDG---DKGKQLYEGREYDYVFSVNLSDDAPNLKLPYNRGEDPWFVAQRFIHKHNLPQAYLD 445

  Fly   451 QVANFIIKNSEGPVLMEQAPTGYQDPFTGGSRYVPGSS---------NT---------------- 490
            ||||||:|||:...:.......|.||||||||||||||         ||
Mosquito   446 QVANFIVKNSDSAPVQSALANSYYDPFTGGSRYVPGSSGGQFQPTAANTDPFTGGSSYTTQTPNV 510

  Fly   491 --------------NMGSGGNVDPFTGASSYSTASSNAQSQVDVNFVRSGDKHFPVSNYRIFDTC 541
                          |.|:|||:|||||.|||:|.|:.         |:..:.|||..:|.:.:..
Mosquito   511 AMAPNAGGAAAAAANGGNGGNLDPFTGGSSYTTGSTE---------VKKSNTHFPHRHYILLENA 566

  Fly   542 DAKKVLEKMIEFNGKLSLPDGRVGEEVLLAVIKLADQ---SPELDLTSLEALAIL-LKWPASMQF 602
            |..|||.|:.|.|.||.....|:.::.|..:::.|.:   ..|.:...|.||..| ..||....|
Mosquito   567 DLSKVLVKLKELNSKLEDQSLRMSDDTLNDIVRYAGEVMTCGEQNSACLTALKFLYTTWPTEKLF 631

  Fly   603 PVLDILRLAVRNEAIFSVLNNSHNFLATVIPQLSGSAPNQLMVVRCLANIMSHAAGRQNVMSRLA 667
            |::||.||.||.......|....:|:.|.:...:....||||..||..|:::|..||..|:..:.
Mosquito   632 PIMDITRLIVREPRACQELFEDASFMGTFLQHTNHLPANQLMSARCFTNMLAHQPGRNVVVEHIR 696

  Fly   668 EIIDLVGAIKTGSA---NLQIAVATFYLNLTISQTLDVAKSEVCHVVTSGIVELLKWAKDLEACY 729
            .|:|.. |:..|||   |||||:|:||||||::|...::..:.|.|:...|.|||.|..|.||.|
Mosquito   697 AIVDRF-AVLRGSACSPNLQIALASFYLNLTMTQLDKLSSVDFCKVLAGTIGELLCWLTDNEATY 760

  Fly   730 RSMQAIGN-LTTTSCGQETIAQVVSVDYVM-DKLRELTITPQDKNFSKVNSVGQAL 783
            |..||:|| |:....|...||..:..:..: ||:. ..|:.:..||.|:|.....|
Mosquito   761 RGYQALGNLLSMPGPGMGAIADTLKGNSALTDKIL-FNISSELPNFGKLNECASYL 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plap	NP_524666.2	WD40	10..305	CDD:238121	157/303 (52%)
		WD40 repeat	23..64	CDD:293791	19/41 (46%)
		WD40 repeat	70..106	CDD:293791	16/43 (37%)
		WD40 repeat	111..149	CDD:293791	18/37 (49%)
		WD40 repeat	156..190	CDD:293791	18/33 (55%)
		WD40 repeat	196..230	CDD:293791	16/33 (48%)
		WD40 repeat	236..277	CDD:293791	19/40 (48%)
		WD40 repeat	284..304	CDD:293791	11/19 (58%)
		PFU	353..462	CDD:462670	68/108 (63%)
		PUL	531..781	CDD:462428	89/258 (34%)
Plap	XP_314716.5	None