Protein Alignment: NtR and HTR3B

• Sequence 1: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_006019.1
• Gene: HTR3B
• HGNCID: 5298
• Length: 441
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 67/343 (20%)
• Similarity: 119/343 (35%)
• Gaps: 97/343 (28%)

  Fly   202 YGSEIAPI---VKEETKTEKLLSH--LNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRM 261
            |..|:.|:   .|..|....|..|  |::.|||                         .:|:|.:
Human    43 YHKEVRPVYNWTKATTVYLDLFVHAILDVDAEN-------------------------QILKTSV 82

  Fly   262 HMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELM--VYANGSI 324
            .....|.|..|.|....|..:.....|...||.|.: ::|..:.     ::.|..:  ||.|.|.
Human    83 WYQEVWNDEFLSWNSSMFDEIREISLPLSAIWAPDI-IINEFVD-----IERYPDLPYVYVNSSG 141

  Fly   325 TLYAQN---LQLASWCVDSARNWPSERVTC------------DIELG-LNGQEGQENVALIYDDQ 373
            |:  :|   :|:.|.|......:|.:...|            |::|. |...|.      |..|:
Human   142 TI--ENYKPIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPED------IQHDK 198

  Fly   374 RKPIAPNEHVNTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVA-IEFTLQRNRSFYMTVF 437
            :..:..:|       |....:|            :...::|...|..| |:|.:...|  :..|:
Human   199 KAFLNDSE-------WELLSVS------------STYSILQSSAGGFAQIQFNVVMRR--HPLVY 242

  Fly   438 YLPLIACQMFLIL----SFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYKVIMM 498
            .:.|:...:||:|    ||.|....|:.::....::..:.:.   |....:.||      :.:..
Human   243 VVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTSVLVGYTVF---RVNMSNQVP------RSVGS 298

  Fly   499 TTTYCYILHICIIWLDL 515
            |....:...||:.:|.|
Human   299 TPLIGHFFTICMAFLVL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	45/238 (19%)
HTR3B	NP_006019.1	LIC	8..435	CDD:273305	67/343 (20%)
		Neur_chan_LBD	33..239	CDD:280998	50/256 (20%)
		Neur_chan_memb	246..>328	CDD:280999	16/80 (20%)
		HA-stretch	381..413

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900