Protein Alignment NtR and Chrna6

DIOPT Version :10

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_476532.2
• Gene: Chrna6 / 81721
• RGDID: 69281
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 87/390 - (22%)
• Similarity: 154/390 - (39%)
• Gaps: 45/390 - (11%)

  Fly   188 SNTARWFYDCGFDGYGSEIAPIVKEETKTEKLLSHLN---IQAENASMPANLSSISFHFQ---TR 246
            |....|.  |||..:.......|.||.....|.:|.|   ...||.|.|     ::.||:   |:
  Rat    12 SGLCLWI--CGFLAFFKGSRGCVSEEQLFHTLFAHYNRFIRPVENVSDP-----VTVHFELAITQ 69

  Fly   247 SLAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVL 311
            ....::.:.:::|.:.:...|:|.||.|.|.::..:|:...|...||||.:.:.|.|:... ||.
  Rat    70 LANVDEVNQIMETNLWLRHVWKDYRLCWDPTEYDGIETLRVPADNIWKPDIVLYNNAVGDF-QVE 133

  Fly   312 QSYELMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKP 376
            ...:.::..:|.|| :.......|.|......:|.:...|.::.|....:..|...||...:
  Rat   134 GKTKALLKYDGVIT-WTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK--- 194

  Fly   377 IAPNEHVNTPSGWSFTQMSVVLVENDSQR-----RYNPKGMMQKMTGDVAIEFTLQRNRSFYMTV 436
                  |:....|..::..:|    |:..     :||   ..:::..|:...|.::|...||...
  Rat   195 ------VDMNDFWENSEWEIV----DASGYKHDIKYN---CCEEIYTDITYSFYIRRLPMFYTIN 246

  Fly   437 FYLPLIACQMFLILSFVLRST--RRSSLILIALLIAAWGLMYMTR-YASPHYVPPMMTAYKVIMM 498
            ..:|.:......:|.|.|.|.  .:.:|.:..||.....|:.:|. ..|...|.|::..|.:..|
  Rat   247 LIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTM 311

  Fly   499 TTTYCYILHICIIWLDLY---PPRSKAPGWLVRVINSNVLRCILGLRFS-DSTDYCDIQENPWHH 559
            ......|: :.:..|:::   |.....|.| |:.:...|...||.:|.. |.|...|..::|..|
  Rat   312 IFVTLSIV-VTVFVLNIHYRTPATHTMPKW-VKTMFLQVFPSILMMRRPLDKTKEADGVKDPKTH 374

  Fly   560  559
              Rat   375  374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	89..191	CDD:463505	1/2 (50%)
		Neur_chan_LBD	212..429	CDD:460752	48/227 (21%)
Chrna6	NP_476532.2	LIC	34..483	CDD:455710	81/366 (22%)
		LGIC_ECD	34..240	CDD:475126	49/228 (21%)