Protein Alignment NtR and nAChRalpha2

DIOPT Version :9

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 76/411 - (18%)
• Similarity: 146/411 - (35%)
• Gaps: 114/411 - (27%)

  Fly   191 ARWFYDCGFDGYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSS 255
            |:..||.....|...|.|:   ...|:.:|..|.::.... :..||.                ..
  Fly    45 AKRLYDDLLSNYNRLIRPV---SNNTDTVLVKLGLRLSQL-IDLNLK----------------DQ 89

  Fly   256 LLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGA-----LQSMGQVLQSYE 315
            :|.|.:.:...|:|.:..|.|.::|.:.....|...||.|.:.:.|.|     :.:|.:.:..|
  Fly    90 ILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHY- 153

  Fly   316 LMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQE----NVALIYD-DQRK 375
                 .|.: ::.......|.|....|.:|.::.||.::.|....:|.:    :::...| |.:.
  Fly   154 -----TGKV-VWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKV 212

  Fly   376 PIAPNEHVNTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFY------- 433
            .|..:.....||    .:..::.|..:...:|.|  ...:...|:....||:|...||
  Fly   213 EIGIDLREYYPS----VEWDILGVPAERHEKYYP--CCAEPYPDIFFNITLRRKTLFYTVNLIIP 271

  Fly   434 --------MTVFYLP--------------LIACQMFLILSFVLRSTRRS----------SLILIA 466
                    :.|||||              |.....||::|.::.||..:          :::|:.
  Fly   272 CVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVG 336

  Fly   467 LLIAAWGLMYMTRYASP--HYVPPMMTAY------KVIMMTTTYCYILHICIIWLDLYPPRSKAP 523
            |.:....::....|..|  |.:.|.:.::      |:::|                      :.|
  Fly   337 LSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLM----------------------RVP 379

  Fly   524 GWLVRVINSNVLRCILGLRFS 544
            ..|:|.:.:|.:.  .||:||
  Fly   380 KDLLRDLAANKIN--YGLKFS 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052	76/411 (18%)
		Neur_chan_LBD	212..429	CDD:280998	40/226 (18%)
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	47/250 (19%)
		LIC	47..544	CDD:273305	75/409 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910