Protein Alignment NtR and chrnd

DIOPT Version :10

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_996947.1
• Gene: chrnd / 404273
• ZFINID: ZDB-GENE-030131-6665
• Length: 518
• Species: Danio rerio
• Alignment Length: 378
• Identity: 75/378 - (19%)
• Similarity: 139/378 - (36%)
• Gaps: 83/378 - (21%)

  Fly   167 LLQFI-------DEAPLVINYLSFSSFGSNTARWFYDCGFDGYGSEIAPIVKEETKTEKLLSHLN 224
            ||.||       :|...:||||            |.:   .||..|:.|:   :.|.|.:..:|.
Zfish    11 LLCFIFQECCGRNEEERLINYL------------FKE---RGYNKELRPV---QNKDETVDIYLA 57

  Fly   225 IQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPD 289
            :...|.                 ::.::....|.|.:.|...|:|.||.|...:: .:.....|.
Zfish    58 LTLSNL-----------------ISLKEVDETLLTNVWMEHGWKDHRLTWNESEY-DIPVLRLPP 104

  Fly   290 LRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDI- 353
            ..:|.|.: ||.....:..||.....:::|::|.: .:.......|.|..:...:|.:...|.:
Zfish   105 SMVWLPEI-VLENNNDAQFQVAYYCNVLIYSSGDM-YWLPPAIFRSSCSINVNYFPFDWQNCSLK 167

  Fly   354 ---------ELGLNGQEGQENVA------LIYDDQRKPIAPNEHVNTPSGWSFTQMSVVLVENDS 403
                     |:.||.:..|||..      :|.|              |.|  ||:.....:.:..
Zfish   168 FSSLTYNAKEISLNLKMEQENTTYYKVEWIIID--------------PEG--FTENGEWEIVHKP 216

  Fly   404 QRRYNPKGMMQKMT--GDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRSTRRSSLIL-I 465
            .||...|.:.::..  .|:.....::|...||:....:|.:.......|.:.|.:.....:.| |
Zfish   217 ARRNIYKSIPKESNKHQDITFYLIIKRKPLFYIVNIIIPCVLISFLASLVYYLPADSGEKMTLSI 281

  Fly   466 ALLIA--AWGLMYMTRYASPHYVPPMMTAYKVIMMTTTYCYILHICIIWLDLY 516
            ::|:|  .:.|:...|........|::..|.:.:|......:|: |:|.|:|:
Zfish   282 SVLLAQSVFLLLISQRLPETSMAVPLIVKYLMFIMVLVTVVVLN-CVIVLNLH 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	89..191	CDD:463505	9/30 (30%)
		Neur_chan_LBD	212..429	CDD:460752	41/234 (18%)
chrnd	NP_996947.1	LGIC_ECD_nAChR_D	26..245	CDD:349829	51/272 (19%)
		Cys-loop	150..164	CDD:349829	2/13 (15%)
		Neur_chan_memb	252..490	CDD:460753	17/83 (20%)