DRSC/TRiP Functional Genomics Resources

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Protein Alignment: NtR and HTR3A

Sequence 1:NP_651958.2 Gene:NtR FlyBaseID:FBgn0029147 Length:585 Species:Drosophila melanogaster
Sequence 2:NP_998786.3 Gene:HTR3A HGNCID:5297 Length:510 Species:Homo sapiens

Alignment Length:359 Identity:64/360 (18%)
Similarity:126/360 (35%) Gaps:102/360 (28%)


  Fly   248 LAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQ 312
            |..::.:.:|.|.:....:|.|..|.|.||||.::.....|...||.|  ::|......:|:...
Human    71 LNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVP--DILINEFVDVGKSPN 133

  Fly   313 SYELMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPI 377
            ...:.:...|.:..| :.||:.:.|.....|:|.:...|.:                        
Human   134 IPYVYIRHQGEVQNY-KPLQVVTACSLDIYNFPFDVQNCSL------------------------ 173

  Fly   378 APNEHVNTPSGWSFTQMSVVL--------VEND-----SQRRYNPKGMMQKMTGDVAIEFTLQRN 429
                   |.:.|..|...:.:        |::|     :|..:...|::....     ||:::.:
Human   174 -------TFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFR-----EFSMESS 226

  Fly   430 RSFYMTVFYLPLIACQMFLILSFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYK 494
            ..:....||:.:....:|.::|.:|     .|:.|:.:.|..:            |:||......
Human   227 NYYAEMKFYVVIRRRPLFYVVSLLL-----PSIFLMVMDIVGF------------YLPPNSGERV 274

  Fly   495 VIMMTTTYCYILHICII------------WLDLYPPRSK-------APGWLVRVINSNVLRCILG 540
            ...:|....|.:.:.|:            .:...||.|:       ||..|:.|..::.|.| .|
Human   275 SFKITLLLGYSVFLIIVSDTLPATAIGTPLIGKAPPGSRAQSGEKPAPSHLLHVSLASALGC-TG 338

  Fly   541 LRFSDSTDYCDIQENPWHHMAKILNNLSSILVII 574
            :.|.    .|         ||.::.:|:..:.|:
Human   339 VYFV----VC---------MALLVISLAETIFIV 359

Known Domains:


GeneSequenceDomainRegion External IDIdentity
NtRNP_651958.2 Methyltransf_FA 90..191 CDD:289052
Neur_chan_LBD 212..429 CDD:280998 34/194 (18%)
HTR3ANP_998786.3 LIC 23..504 CDD:273305 64/360 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG3645
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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