Protein Alignment: NtR and HTR3E

• Sequence 1: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001243543.1
• Gene: HTR3E
• HGNCID: 24005
• Length: 482
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 62/381 (16%)
• Similarity: 112/381 (29%)
• Gaps: 144/381 (38%)

  Fly   229 NASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIW 293
            |.|:|..: :|||          ..|::|.      :.|.:..:.|.||:...:.........:|
Human    74 NISVPTQV-NISF----------AMSAILD------VVWDNPFISWNPEECEGITKMSMAAKNLW 121

  Fly   294 KPHMNVLN------------------------GALQSMGQVLQSYELMVYANGSITLYAQNLQLA 334
            .|.:.::.                        |.|..:.:..:.....|...|.|. |.:.:::.
Human   122 LPDIFIIELCVSRAGQREVPSPGSHRDHSLPLGPLMDVDKTPKGLTAYVSNEGRIR-YKKPMKVD 185

  Fly   335 SWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYD------DQRKPIAPNEHVNTPSGWSFTQ 393
            |.|......:|.::..|.:...          :.:|.      |..|.:           |..|.
Human   186 SICNLDIFYFPFDQQNCTLTFS----------SFLYTVDSMLLDMEKEV-----------WEITD 229

  Fly   394 MSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFY-MTVFYLPLIACQMFLILSFVLRST 457
            .|..:::...:         .::.|.......|.|..:.| ..|||:.:               .
Human   230 ASRNILQTHGE---------WELLGLSKATAKLSRGGNLYDQIVFYVAI---------------R 270

  Fly   458 RRSSLILIAL------LIAAWGLMYMTRYASPHYVP---PMMTAYKVIMM--------------- 498
            ||.||.:|.|      |:|...|.:.....|.:.||   .::..|.|.::
Human   271 RRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITLLLGYNVFLLMMSDLLPTSGTPLIG 335

  Fly   499 ----------------TTTYCYILHICIIWLDLYPPRSKAPGWLVRVINSNVLRC 537
                            |....::||:.    ...||  ..|.||    :|.:|.|
Human   336 VYFALCLSLMVGSLLETIFITHLLHVA----TTQPP--PLPRWL----HSLLLHC 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	33/230 (14%)
HTR3E	NP_001243543.1	Neur_chan_LBD	70..273	CDD:280998	39/262 (15%)
		Neur_chan_memb	280..>379	CDD:280999	19/109 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900