Protein Alignment NtR and Chrnb4

DIOPT Version :10

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_434693.1
• Gene: Chrnb4 / 25103
• RGDID: 2351
• Length: 495
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 72/326 - (22%)
• Similarity: 128/326 - (39%)
• Gaps: 67/326 - (20%)

  Fly   217 EKLLSHL--NIQAENASMPANLSS--ISFHFQ---TRSLAYEQTSSLLQTRMHMMMHWRDSRLVW 274
            |||:..|  ..:..|...||..||  ||...:   ::.::..:...::.|.:.:...|.|.||.|
  Rat    27 EKLMDDLLNKTRYNNLIRPATSSSQLISIRLELSLSQLISVNEREQIMTTSIWLKQEWTDYRLAW 91

  Fly   275 KPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVY------ANGSI-----TLY- 327
            ....:..:.....|..|:|.|.:.:.|.|       ..:||:.||      :||||     .:|
  Rat    92 NSSCYEGVNILRIPAKRVWLPDIVLYNNA-------DGTYEVSVYTNVIVRSNGSIQWLPPAIYK 149

  Fly   328 -AQNLQLASW------CVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNEHVNT 385
             |..:::..:      |....|:|..:....|:.|        ::...|.||           .|
  Rat   150 SACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVL--------KSPTAIMDD-----------FT 195

  Fly   386 PSG-WSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLI 449
            ||| |.       :|....:|..||:   .....||..:|.::|...||.....:|.:......|
  Rat   196 PSGEWD-------IVALPGRRTVNPQ---DPSYVDVTYDFIIKRKPLFYTINLIIPCVLITSLAI 250

  Fly   450 LSFVLRST--RRSSLILIALLIAAWGLMYMTRYASPHYVP-PMMTAYKVI-MMTTTYCYILHICI 510
            |.|.|.|.  .:.:|.:..||...:.|:.:::...|..:. |::..|.:. |:..|:..:..:|:
  Rat   251 LVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDIPLIGKYLLFTMVLVTFSIVTTVCV 315

  Fly   511 I 511
            :
  Rat   316 L 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	89..191	CDD:463505
		Neur_chan_LBD	212..429	CDD:460752	53/238 (22%)
Chrnb4	NP_434693.1	LIC	21..483	CDD:455710	72/326 (22%)
		LGIC_ECD	53..230	CDD:475126	44/212 (21%)