DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NtR and glra3

DIOPT Version :9

Sequence 1:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021333244.1	Gene:	glra3 / 192124	ZFINID:	ZDB-GENE-020402-1	Length:	489	Species:	Danio rerio

Alignment Length:	306	Identity:	67/306 - (21%)
Similarity:	122/306 - (39%)	Gaps:	69/306 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 GYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMM 265
            ||.:.|.|               |.:....::..|:...||    .|:|  :|:...:..:.:..
Zfish    56 GYDARIRP---------------NFKGPPVNVTCNIFINSF----GSIA--ETTMDYRVNIFLRQ 99

  Fly   266 HWRDSRLVWK--PEDFGSLESFEHPDL--RIWKPHMNVLNGALQSMGQVLQSYELM-VYANGSIT 325
            .|.|.||.:.  |:|...|:    |.:  .||||.:...|.......:|....:|: ::.||::
Zfish   100 KWNDPRLAYSEYPDDSLDLD----PSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNV- 159

  Fly   326 LYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRK-PIAPNEHVNTPSGW 389
            ||:..|.|...|....:|:|.:..||.::|...|....:   ||::.|.| |:...:.:..|.
Zfish   160 LYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMND---LIFEWQEKGPVQVADGLTLPQ-- 219

  Fly   390 SFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVL 454
                   .:::::|..||..|.........:.:.|.|:|...:|:...|:|
Zfish   220 -------FILKDESDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIP-------------- 263

  Fly   455 RSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYKVIMMTT 500
                  ||:::   |.:|...::...|:|..|...:|.  |:.|||
Zfish   264 ------SLLIV---ILSWVSFWINMDAAPARVALGITT--VLTMTT 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	47/222 (21%)
glra3	XP_021333244.1	LIC	13..478	CDD:273305	67/306 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910