Protein Alignment NtR and lgc-13

DIOPT Version :10

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_510023.2
• Gene: lgc-13 / 187971
• WormBaseID: WBGene00011354
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 400
• Identity: 69/400 - (17%)
• Similarity: 135/400 - (33%)
• Gaps: 104/400 - (26%)

  Fly   140 YDPTPIEIVQNQNGELFVYIPGFKKEPLLQFIDEAPLVINYLSFSSFGSNTARWFYDCGFDGYGS 204
            |||.             :|:|.::               :||  .:.|:.||..     |..|..
 Worm    19 YDPQ-------------LYVPKYR---------------DYL--EAQGNLTADL-----FKNYEK 48

  Fly   205 EIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWRD 269
            :::| |.....|.|.|.:      :...|...:...|.:..:.:...:....:...:.:|.:|.|
 Worm    49 DVSP-VYAWFDTSKPLGY------DPDAPQRYNYTLFLYNLKLIQVNEPEEQVSVVLELMEYWYD 106

  Fly   270 SRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVL----QSYELMVYAN-GSITLYAQ 329
            .||.|...|:.::.:......:||.|.:...     .:.:::    |.:.|:...| |.|..|.
 Worm   107 PRLSWNASDYKNVTAIFTRQEKIWSPTLTPF-----GVNEIIDFRDQDFRLVCIDNLGMIYDYL- 165

  Fly   330 NLQLASWCVDSARNWPSERVTCDIELGL------------NGQEGQENVALIYDDQRKPIAPNEH 382
            ::::::.|......:|.:..||.|...|            ...||..|.::.            .
 Worm   166 SVRVSANCRMDVTKFPFDSQTCQIRFSLPIFSYLEVKIYTELYEGINNYSMF------------E 218

  Fly   383 VNTPSGW---SFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAI-EFTLQRNRSFYMTVFYLPLIA 443
            |...|.|   :.|.....|..||            :...::|: |..:.||..:|..:...|...
 Worm   219 VMGNSEWELINLTNRVDFLTYND------------RFDVELAVYEIKIARNPLYYFYMIVFPSFV 271

  Fly   444 CQMFLILSFVLRSTRRSSLILIALLIAAWGLMYMTRY--ASPHYVP-----PMMTAYKVIMMTTT 501
            .....|:...::...:.|.:.:.|.    .:|.||..  .....:|     |::..|.::.:...
 Worm   272 INSVSIVGVFIKGADKMSRLNVGLT----NIMTMTFILGVMSDKIPRTGNVPLLGIYIIVNLLIM 332

  Fly   502 YCYILHICII 511
            ...|:.:.||
 Worm   333 LVAIIIVTII 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	89..191	CDD:463505	8/50 (16%)
		Neur_chan_LBD	212..429	CDD:460752	39/237 (16%)
lgc-13	NP_510023.2	LGIC_ECD_cation	74..257	CDD:349790	35/212 (17%)
		Cys-loop	173..187	CDD:349790	2/13 (15%)
		LGIC_TM	259..>335	CDD:476813	11/79 (14%)
		TM1 helix	263..284	CDD:349850	2/20 (10%)
		TM2 helix	292..313	CDD:349850	4/24 (17%)