DRSC/TRiP Functional Genomics Resources

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Protein Alignment: NtR and CHRNB1

Sequence 1:NP_651958.2 Gene:NtR FlyBaseID:FBgn0029147 Length:585 Species:Drosophila melanogaster
Sequence 2:NP_000738.2 Gene:CHRNB1 HGNCID:1961 Length:501 Species:Homo sapiens

Alignment Length:387 Identity:81/388 (21%)
Similarity:147/388 (38%) Gaps:56/388 (14%)


  Fly   203 GSEIAPIVK----EETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSL------L 257
            |:.:||.|:    |....|||.|..:.....|....:...:|.     .|...|..||      :
Human    14 GAPLAPGVRGSEAEGRLREKLFSGYDSSVRPAREVGDRVRVSV-----GLILAQLISLNEKDEEM 73

  Fly   258 QTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANG 322
            .|::::.:.|.|.||.|.|.:...::|.......:|.|.:.:||.. .....|.....::|.::|
Human    74 STKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNN-DGNFDVALDISVVVSSDG 137

  Fly   323 SIT-----LYAQNLQLA------SW--C--VDSARNWPSERVTCDIELGLNGQEGQENVALIYDD 372
            |:.     :|..:..:.      .|  |  |.|:.::.|..|:....||.:||..||        
Human   138 SVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQE-------- 194

  Fly   373 QRKPIAPNEHVNTPSG-WSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTV 436
                |..:|.....:| |........|::...    :|:|..:....:|.....::|...||:..
Human   195 ----IHIHEGTFIENGQWEIIHKPSRLIQPPG----DPRGGREGQRQEVIFYLIIRRKPLFYLVN 251

  Fly   437 FYLPLIACQMFLILSFVL--RSTRRSSLILIALL-IAAWGLMYMTRYASPHYVPPMMTAYKVI-M 497
            ...|.|...:..|..|.|  .:..:..|.:.||| :..:.|:...:........|::..|.:. |
Human   252 VIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTM 316

  Fly   498 MTTTYCYILHICIIWLDLYPPRS-KAPGWLVRVINSNVLRCILGLRFSDSTDYCDIQENPWH 558
            :..|:..||.:.::.|....|.: :.|.|:.::.   :.:..|.||........|:...|.|
Human   317 VLVTFSVILSVVVLNLHHRSPHTHQMPLWVRQIF---IHKLPLYLRLKRPKPERDLMPEPPH 375

Known Domains:


GeneSequenceDomainRegion External IDIdentity
NtRNP_651958.2 Methyltransf_FA 90..191 CDD:289052
Neur_chan_LBD 212..429 CDD:280998 49/239 (21%)
CHRNB1NP_000738.2 Neur_chan_LBD 27..245 CDD:308532 49/240 (20%)
Neur_chan_memb 252..487 CDD:308533 26/128 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG3645
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR18945
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.000

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