Protein Alignment: NtR and CHRNB1

• Sequence 1: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_000738.2
• Gene: CHRNB1
• HGNCID: 1961
• Length: 501
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 81/388 (21%)
• Similarity: 147/388 (38%)
• Gaps: 56/388 (14%)

  Fly   203 GSEIAPIVK----EETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSL------L 257
            |:.:||.|:    |....|||.|..:.....|....:...:|.     .|...|..||      :
Human    14 GAPLAPGVRGSEAEGRLREKLFSGYDSSVRPAREVGDRVRVSV-----GLILAQLISLNEKDEEM 73

  Fly   258 QTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANG 322
            .|::::.:.|.|.||.|.|.:...::|.......:|.|.:.:||.. .....|.....::|.::|
Human    74 STKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNN-DGNFDVALDISVVVSSDG 137

  Fly   323 SIT-----LYAQNLQLA------SW--C--VDSARNWPSERVTCDIELGLNGQEGQENVALIYDD 372
            |:.     :|..:..:.      .|  |  |.|:.::.|..|:....||.:||..||
Human   138 SVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQE-------- 194

  Fly   373 QRKPIAPNEHVNTPSG-WSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTV 436
                |..:|.....:| |........|::...    :|:|..:....:|.....::|...||:..
Human   195 ----IHIHEGTFIENGQWEIIHKPSRLIQPPG----DPRGGREGQRQEVIFYLIIRRKPLFYLVN 251

  Fly   437 FYLPLIACQMFLILSFVL--RSTRRSSLILIALL-IAAWGLMYMTRYASPHYVPPMMTAYKVI-M 497
            ...|.|...:..|..|.|  .:..:..|.:.||| :..:.|:...:........|::..|.:. |
Human   252 VIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTM 316

  Fly   498 MTTTYCYILHICIIWLDLYPPRS-KAPGWLVRVINSNVLRCILGLRFSDSTDYCDIQENPWH 558
            :..|:..||.:.::.|....|.: :.|.|:.::.   :.:..|.||........|:...|.|
Human   317 VLVTFSVILSVVVLNLHHRSPHTHQMPLWVRQIF---IHKLPLYLRLKRPKPERDLMPEPPH 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	49/239 (21%)
CHRNB1	NP_000738.2	Neur_chan_LBD	27..245	CDD:308532	49/240 (20%)
		Neur_chan_memb	252..487	CDD:308533	26/128 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000