DRSC/TRiP Functional Genomics Resources

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Protein Alignment: NtR and CHRNA3

Sequence 1:NP_651958.2 Gene:NtR FlyBaseID:FBgn0029147 Length:585 Species:Drosophila melanogaster
Sequence 2:NP_000734.2 Gene:CHRNA3 HGNCID:1957 Length:505 Species:Homo sapiens

Alignment Length:345 Identity:69/346 (20%)
Similarity:138/346 (40%) Gaps:34/346 (10%)


  Fly   206 IAPIVKEETKTEKLLSHLNIQAENASMP-ANLSS-ISFHFQ---TRSLAYEQTSSLLQTRMHMMM 265
            :.|:.:......:|...|.........| ||:|. :..||:   ::.:..::.:.:::|.:.:..
Human    25 LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQ 89

  Fly   266 HWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQN 330
            .|.|.:|.|.|.|:|..|....|..:||||.:.:.|.|:... ||....:.::...|.:|.....
Human    90 IWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPA 153

  Fly   331 LQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQR-KPIAPNEHVNTPSGWSFTQM 394
            : ..|.|......:|.:...|.::.|          :..||..: ..:.....:|....|...:.
Human   154 I-FKSSCKIDVTYFPFDYQNCTMKFG----------SWSYDKAKIDLVLIGSSMNLKDYWESGEW 207

  Fly   395 SVVLV---ENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRS 456
            :::..   ::|.  :||   ..:::..|:.....::|...||.....:|.:......:|.|.|.|
Human   208 AIIKAPGYKHDI--KYN---CCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPS 267

  Fly   457 T--RRSSLILIALLIAAWGLMYMTR-YASPHYVPPMMTAYKVIMMTTTYCYILHICIIWLDLY-- 516
            .  .:.:|.:..||.....|:.:|. ..|...|.|::..|.:..|......|: |.:..|:::  
Human   268 DCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIV-ITVFVLNVHYR 331

  Fly   517 -PPRSKAPGWLVRVINSNVL 535
             |.....|.| |:.:..|:|
Human   332 TPTTHTMPSW-VKTVFLNLL 350

Known Domains:


GeneSequenceDomainRegion External IDIdentity
NtRNP_651958.2 Methyltransf_FA 90..191 CDD:289052
Neur_chan_LBD 212..429 CDD:280998 42/226 (19%)
CHRNA3NP_000734.2 Neur_chan_LBD 30..496 CDD:332142 68/341 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG3645
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR18945
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.000

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