Protein Alignment: NtR and CHRNA3

• Sequence 1: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_000734.2
• Gene: CHRNA3
• HGNCID: 1957
• Length: 505
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 69/346 (20%)
• Similarity: 138/346 (40%)
• Gaps: 34/346 (10%)

  Fly   206 IAPIVKEETKTEKLLSHLNIQAENASMP-ANLSS-ISFHFQ---TRSLAYEQTSSLLQTRMHMMM 265
            :.|:.:......:|...|.........| ||:|. :..||:   ::.:..::.:.:::|.:.:..
Human    25 LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQ 89

  Fly   266 HWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQN 330
            .|.|.:|.|.|.|:|..|....|..:||||.:.:.|.|:... ||....:.::...|.:|.....
Human    90 IWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPA 153

  Fly   331 LQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQR-KPIAPNEHVNTPSGWSFTQM 394
            : ..|.|......:|.:...|.::.|          :..||..: ..:.....:|....|...:.
Human   154 I-FKSSCKIDVTYFPFDYQNCTMKFG----------SWSYDKAKIDLVLIGSSMNLKDYWESGEW 207

  Fly   395 SVVLV---ENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRS 456
            :::..   ::|.  :||   ..:::..|:.....::|...||.....:|.:......:|.|.|.|
Human   208 AIIKAPGYKHDI--KYN---CCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPS 267

  Fly   457 T--RRSSLILIALLIAAWGLMYMTR-YASPHYVPPMMTAYKVIMMTTTYCYILHICIIWLDLY-- 516
            .  .:.:|.:..||.....|:.:|. ..|...|.|::..|.:..|......|: |.:..|:::
Human   268 DCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIV-ITVFVLNVHYR 331

  Fly   517 -PPRSKAPGWLVRVINSNVL 535
             |.....|.| |:.:..|:|
Human   332 TPTTHTMPSW-VKTVFLNLL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	42/226 (19%)
CHRNA3	NP_000734.2	Neur_chan_LBD	30..496	CDD:332142	68/341 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000