Protein Alignment: NtR and CHRNA2

• Sequence 1: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_000733.2
• Gene: CHRNA2
• HGNCID: 1956
• Length: 529
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 76/365 (21%)
• Similarity: 145/365 (40%)
• Gaps: 35/365 (10%)

  Fly   214 TKTE-KLLSHL----NIQAENASMPANLSSISFHFQTRSLA-YEQTSSLLQTRMHMMMHWRDSRL 272
            |:|| :|..||    |..|......:::..:.|......|. .::.:.::.|.:.:...|.|.:|
Human    56 TETEDRLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL 120

  Fly   273 VWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQLASWC 337
            .|.|.|||::.|...|...||.|.:.:.|.| .....|....:..:::.|::......:..:|..
Human   121 RWNPTDFGNITSLRVPSEMIWIPDIVLYNNA-DGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCS 184

  Fly   338 VDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNEH-VNTPSGWSFTQMSVVLVEN 401
            :| ...:|.::..|.::.|          :..||..:..:...|. |:....|...:.::|
Human   185 ID-VTFFPFDQQNCKMKFG----------SWTYDKAKIDLEQMEQTVDLKDYWESGEWAIV---- 234

  Fly   402 DSQRRYNPK--GMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRST--RRSSL 462
            ::...||.|  ....::..||...|.::|...||.....:|.:......:|.|.|.|.  .:.:|
Human   235 NATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITL 299

  Fly   463 ILIALLIAAWGLMYMTR-YASPHYVPPMMTAYKVIMMTTTYCYILHICIIWLDLY---PPRSKAP 523
            .:..||.....|:.:|. ..|...|.|::..|.:..|......|: |.:..|:::   |.....|
Human   300 CISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIV-ITVFVLNVHHRSPSTHTMP 363

  Fly   524 GWLVRVINSNVLRCILGLRFSDSTDYCD---IQENPWHH 559
            .|:...:...|.|.:|..|.....:.|.   ::.:|.:|
Human   364 HWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYH 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	46/224 (21%)
CHRNA2	NP_000733.2	LIC	57..522	CDD:273305	75/364 (21%)
		Neur_chan_LBD	59..265	CDD:280998	44/222 (20%)
		Neur_chan_memb	272..520	CDD:280999	28/133 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000