Protein Alignment NtR and Chrna3

DIOPT Version :9

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_660111.3
• Gene: Chrna3 / 110834
• MGIID: 87887
• Length: 499
• Species: Mus musculus
• Alignment Length: 382
• Identity: 76/382 - (19%)
• Similarity: 143/382 - (37%)
• Gaps: 48/382 - (12%)

  Fly   176 LVINYLSFSSFGSNTARWFYDCGFDGYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSIS 240
            ||:..|..:| .|......:...|:.|...|.|:.                  |.|.|.   .|.
Mouse    15 LVLMLLPVAS-ASEAEHRLFQYLFEDYNEIIRPVA------------------NVSHPV---IIQ 57

  Fly   241 FHFQTRSLA-YEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGAL 304
            |......|. .::.:.:::|.:.:...|.|.:|.|||.|:..:|....|..:||||.:.:.|.|
Mouse    58 FEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNA- 121

  Fly   305 QSMGQVLQSYELMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALI 369
            ....||....:.::...|.:|.....: ..|.|......:|.:...|.::.|          :..
Mouse   122 DGDFQVDDKTKALLKYTGEVTWIPPAI-FKSSCKIDVTYFPFDYQNCTMKFG----------SWS 175

  Fly   370 YDDQR-KPIAPNEHVNTPSGWSFTQMSVVLVEN-DSQRRYNPKGMMQKMTGDVAIEFTLQRNRSF 432
            ||..: ..:.....:|....|...:.:::.... ..:.:||   ..:::..|:.....::|...|
Mouse   176 YDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYN---CCEEIYQDITYSLYIRRLPLF 237

  Fly   433 YMTVFYLPLIACQMFLILSFVLRST--RRSSLILIALLIAAWGLMYMTR-YASPHYVPPMMTAYK 494
            |.....:|.:......:|.|.|.|.  .:.:|.:..||.....|:.:|. ..|...|.|::..|.
Mouse   238 YTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYL 302

  Fly   495 VIMMTTTYCYILHICIIWLDLY---PPRSKAPGWLVRVINSNVLRCILGLRFSDSTD 548
            :..|......|: |.:..|:::   |.....|.| |:.:..|:|..::.:....||:
Mouse   303 LFTMIFVTLSIV-ITVFVLNVHYRTPTTHTMPTW-VKAVFLNLLPRVMFMTRPTSTE 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052	5/14 (36%)
		Neur_chan_LBD	212..429	CDD:280998	38/219 (17%)
Chrna3	NP_660111.3	LIC	24..490	CDD:273305	73/373 (20%)
		LGIC_ECD_nAChR_A3	29..235	CDD:349817	43/241 (18%)
		Cys-loop	153..167	CDD:349817	2/13 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810