DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NtR and chrng

DIOPT Version :9

Sequence 1:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001241879.1	Gene:	chrng / 100536659	ZFINID:	ZDB-GENE-030131-3805	Length:	540	Species:	Danio rerio

Alignment Length:	373	Identity:	66/373 - (17%)
Similarity:	134/373 - (35%)	Gaps:	83/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 GYGSEIAPIVKEE----TKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRM 261
            ||...|.|:...|    .|.:..|::|                        ::..:....|.|.:
Zfish    37 GYNKNIRPVESHEDIIDVKIKMTLTNL------------------------ISLNEKEETLTTCV 77

  Fly   262 HMMMHWRDSRLVWKP----EDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYAN- 321
            .:.|.|||.||.|..    |.:.::.....|...||.|.:.:.|       .|...:|:.:|||
Zfish    78 WIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLEN-------NVDGRFEVALYANT 135

  Fly   322 -----GSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNE 381
                 ||:......:..:| |......:|.:...|.:..........|...::.|:.
Zfish   136 LIDPDGSVYWLPPAIYRSS-CAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLSDED-------- 191

  Fly   382 HVNTPSGW------SFTQMSVVLVENDS-----QRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMT 435
              |....|      :||:....::::..     .:||.|..:..:   ::.....:||...||:.
Zfish   192 --NVTMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELEHQ---EIIFFLIIQRKPLFYVI 251

  Fly   436 VFYLPLIACQMFLILSFVL-----RSTRRSSLILIALLIAAWGLMYMTRYASPH--YVPPMMTAY 493
            ...:|   |.:|..|..::     ::..:...:.|.:|:.....:::.....|.  ...|::..|
Zfish   252 NIIVP---CVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKY 313

  Fly   494 KVIMMTTTYCYILHICIIWLD--LYPPRSKAPGWLVRVINSNVLRCIL 539
            .:.:|:.|...::: |::.|:  |..|.:......:|.:..|:|..:|
Zfish   314 LMFVMSVTTITVMN-CVVVLNVSLRTPNTHPMSNTIRKVLLNILPRVL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	40/241 (17%)
chrng	NP_001241879.1	LIC	21..511	CDD:273305	66/373 (18%)
		Neur_chan_LBD	27..246	CDD:280998	45/253 (18%)
		Neur_chan_memb	253..509	CDD:280999	19/112 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900