DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fal and LOC572225

DIOPT Version :9

Sequence 1:	NP_001137974.1	Gene:	fal / 43927	FlyBaseID:	FBgn0028380	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001373580.1	Gene:	LOC572225 / 572225	-ID:	-	Length:	499	Species:	Danio rerio

Alignment Length:	275	Identity:	55/275 - (20%)
Similarity:	88/275 - (32%)	Gaps:	91/275 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEDEVH----GVIELSS----------------HIQEIVEHPLFQRLKHVHQ---LGLLPWAIDK 44
            ::.|.|    |.:..||                |..|..:|...::...||:   .|..|:
Zfish   240 VKKEFHCELCGKVSFSSGNLKTHMKTHTKEKPFHCSECDKHFSTKQSMMVHKRIHTGERPY---- 300

  Fly    45 KADHKRYDHCLGAYKSA---QDHLRAIERNSHYEPKLPDWCRQAVE-----IAALLHDIGHGPMS 101
                 :..||:..::..   :.|:|     ||...: |..|.:..:     |..:.|...|....
Zfish   301 -----KCPHCVKTFRDGSHFKTHMR-----SHASER-PYQCSECGKTFKQPICLISHQKIHSEKM 354

  Fly   102 H-------AWELVTH---HEFDHE-ENAMAC--VDKIFKDALNQELVSLRDDGG---------GR 144
            |       .:..:.|   ||..|. |....|  ..|.|.|..:.. |..|...|         ||
Zfish   355 HQCLQCDKRFRQIAHLKRHERMHSGEKPYLCFHCGKSFSDPAHFR-VHQRVHTGERPYHCSVCGR 418

  Fly   145 G----VQLIKALILGSSENLPFPMLGHTYIF---DI--VHNR--------RCGLDVDKWDYL--- 189
            .    ..|:|...:.:.|. ||.......:|   |:  :|.|        .|.:..:::.||
Zfish   419 SFRQHTNLLKHKRIHTGER-PFKCSHCDKMFARSDVLKIHERVHTGEKPYHCSICGERFAYLGGF 482

  Fly   190 -RRDNKRLKILSSAE 203
             ...||.:|...:||
Zfish   483 QTHQNKHVKEQPAAE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fal	NP_001137974.1	HDc	48..210	CDD:238032	43/207 (21%)
LOC572225	NP_001373580.1	COG5048	171..>474	CDD:227381	48/250 (19%)
		C2H2 Zn finger	190..210	CDD:275368
		C2H2 Zn finger	218..238	CDD:275368
		C2H2 Zn finger	246..266	CDD:275368	3/19 (16%)
		C2H2 Zn finger	274..294	CDD:275368	4/19 (21%)
		C2H2 Zn finger	302..322	CDD:275368	4/24 (17%)
		C2H2 Zn finger	330..350	CDD:275368	3/19 (16%)
		C2H2 Zn finger	357..377	CDD:275368	3/19 (16%)
		C2H2 Zn finger	385..405	CDD:275368	6/20 (30%)
		C2H2 Zn finger	413..433	CDD:275368	4/19 (21%)
		C2H2 Zn finger	441..461	CDD:275368	4/19 (21%)
		C2H2 Zn finger	469..489	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960