DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fal and samhd1

DIOPT Version :9

Sequence 1:	NP_001137974.1	Gene:	fal / 43927	FlyBaseID:	FBgn0028380	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_031750194.1	Gene:	samhd1 / 100498574	XenbaseID:	XB-GENE-976503	Length:	630	Species:	Xenopus tropicalis

Alignment Length:	357	Identity:	99/357 - (27%)
Similarity:	162/357 - (45%)	Gaps:	65/357 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LIEDEVHGVIELSSHIQEIVEHPLFQRLKHVHQLG----LLPWAIDKKADHKRYDHCLGAYKSAQ 62
            :..|.:||.|||...:..|::.|.||||:::.|||    :.|     .|.|.|::|.:|....|.
Frog   114 VFNDPIHGHIELHPLLVRIIDTPEFQRLRYIKQLGGSYYVFP-----GASHNRFEHSIGVGYLAG 173

  Fly    63 DHLRAIERNSHYEPKLPDWCRQ--AVEIAALLHDIGHGPMSHAWE------LVTHHEFDHEENAM 119
            ..::|:...   :|:|....|.  .|:||.|.||:||||.||.::      .....:|.||..::
Frog   174 CLVQALHER---QPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASV 235

  Fly   120 ACVDKIFK-----DALNQELVSLRDDGGGRGVQLIKALILG-----------SSEN-LPFPMLGH 167
            |..|.:.|     :.:.:..:.|.||     :..||..|.|           ||:| ..:|..|.
Frog   236 AMFDHLIKSNGLEEVMKEYGLCLPDD-----LTFIKEQIAGPLSSEDEQQFNSSQNSSSWPYRGR 295

  Fly   168 T----YIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEMDFDDVFLQARISPDGQR--IEYRY 226
            |    ::::||.|:|.|:|||||||..||...|.|.::  .|:......||:...|.:  |..|.
Frog   296 TEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN--FDYKRFLKFARVCEVGSKKHICTRD 358

  Fly   227 ADYHRVYRLFEARSLLHVKAYQYPLTCAMDVIFVSVVQRIAPELLSIRSKDPK------------ 279
            .:...:|.:|..|:.||.:|||:.:...::.:......:..|. :.|:..|..
Frog   359 KEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAFIKADPH-IRIKGSDGNYYTISGSVDDMV 422

  Fly   280 -WLELTDEYVLNVIEKD-PISRYVKEPHRLVE 309
             :.:|||....:::..| |..:..:|..|.||
Frog   423 AYTKLTDNIYHHILYSDNPDLKEAREILRKVE 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fal	NP_001137974.1	HDc	48..210	CDD:238032	57/190 (30%)
samhd1	XP_031750194.1	SAM_HD	40..107	CDD:188907
samhd1	XP_031750194.1	YdhJ	112..>474	CDD:224004	99/357 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5060
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426111at33208
OrthoFinder	1	1.000	-	-		FOG0002596
OrthoInspector	1	1.000	-	-		otm48384
Panther	1	1.100	-	-	LDO	PTHR11373
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1701
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.160