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Protein Alignment jim and ZNF628

DIOPT Version :10

Sequence 1:	NP_001262221.1	Gene:	jim / 43924	FlyBaseID:	FBgn0027339	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_149104.3	Gene:	ZNF628 / 89887	HGNCID:	28054	Length:	1059	Species:	Homo sapiens

Alignment Length:	1027	Identity:	220/1027 - (21%)
Similarity:	301/1027 - (29%)	Gaps:	454/1027 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 GRTGNGPGRPHK-----------------NKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDAR 355
            |.||.   ||::                 ...|:.||.|.|..||..||..|....|.|.||..|
Human    85 GHTGE---RPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFICGQCGLAFKWSSHYQYHLRQHTGER 146

  Fly   356 PFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGK 420
            |:||.:|.|.|:..|.|.:|..:|..|:|:||..|.:||.|...|.||.|:|:||:||.||.|.|
Human   147 PYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPK 211

  Fly   421 HFRQKAILNQHVRTH-------------------------------QDVSPH------------- 441
            .|...:.|..|.|||                               :.:.||
Human   212 TFTHSSNLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPP 276

  Fly   442 ----------------LIFK----------------------------------NGPHPTLWPSD 456
                            |:::                                  ..|.....||.
Human   277 PVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQPPSP 341

  Fly   457 VPFP----------------GEDNDTKGDIA------GTGGG----------------------- 476
            :|.|                |:...|...::      |..||
Human   342 LPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQ 406

  Fly   477 -YHDEDSQGTP----------------------------------------------DGSGGMHY 494
             :.:|.:.|.|                                              .||.|:.|
Human   407 CHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLRY 471

  Fly   495 PSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECG 559
              :.:|            |.|.||      .:|..|.|.||:.:.|..|..:|...|.:.|.:||
Human   472 --HLRD------------HTGERP------YQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCG 516

  Fly   560 KRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAIL 624
            ..|:..||...|||:|:.|:|:.|..|.:.||..:.|.:|..:||||:|:.||.|||.|.|.:.|
Human   517 LTFKWSSHYQYHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERPHACGVCGKSFAQTSNL 581

  Fly   625 DQHTRTHQGDRPFCCPM--------------------------PNCRRRFATENEVTKHIDNHMN 663
            .||.|.|.|:|||.||:                          |.|.|.|.....:.:|:..|..
Human   582 RQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAYLQRHLRTHAP 646

  Fly   664 PNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLM-----------NDAKSLA--- 714
            .||...........|........:.....|.     ..|..||.           ..|.||.
Human   647 ANTPPSTTAPAAGPQPPAPLAAARAPPATQD-----VHVLPHLQATLSLEVAGGTAQAPSLGPAA 706

  Fly   715 --AQQFLNNNN-------PSAVD----------NKANILPVRSI--------------------- 739
              :|.||....       ||:|.          .|..:||..|.
Human   707 PNSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPPKLILLPSSSAGAGGGRARQGPRAVGKAGQGA 771

  Fly   740 --------------------ASNAAAAAVVQQSVVKNELYFPQCYGP------------------ 766
                                ||....:.:|.|:|...|.      ||
Human   772 GVVWLPGPGGLGVQGAASAGASGTGQSLIVLQNVGGGEA------GPQEMSGVQLQPLRPAPEVT 830

  Fly   767 -----PFQHPFQAQQQQAQ-------QPS--------------VAHANGGPTPPVTVTVANSVAS 805
                 |.|.....|.|.||       ||:              :::::||       .||....:
Human   831 TVQLQPAQEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPVAGQLSNSSGG-------AVATEAPN 888

  Fly   806 GVVVQQNASASVVAQXHPTTAATG-------------------------------AQQQQPSAPQ 839
            .:|||..|:..::.. .|..|..|                               .:|.:....:
Human   889 LLVVQSGAAEELLTGPGPGEAGDGEASTGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQE 953

  Fly   840 QQHHPP----PP---PPTSTAHHIASAAAAVTAVTPSSAHASPVAAPQTVTLSITLPPP--PASH 895
            .:..||    ||   ||......|.||.|  |.:..||.     ....|.||.:..|||  |||
Human   954 VETLPPGLTEPPATGPPGQKLLIIRSAPA--TELLDSSN-----TGGGTATLQLLAPPPSGPAS- 1010

  Fly   896 TVHPGHPGHPGHPG------VANGAAP--------PPPTLSHAIPIHPHIHS 933
                |..|.||.|.      |..||.|        |...:...:|....:|:
Human  1011 ----GPAGLPGAPASQMVQVVPAGAGPGVMTPQGLPSIQIVQTLPAVQLVHT 1058

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.