Protein Alignment Atf3 and FOSL2

DIOPT Version :10

• Sequence 1: NP_001259125.1
• Gene: Atf3 / 43867
• FlyBaseID: FBgn0028550
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: XP_006712039.1
• Gene: FOSL2 / 2355
• HGNCID: 3798
• Length: 343
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 65/271 - (23%)
• Similarity: 110/271 - (40%)
• Gaps: 86/271 - (31%)

  Fly   200 LTPEDEDRRRRRRERNKIAATKCRMKKRERTQNL-----------------IKESEVLDTQNVEL 247
            |:||:|::||.||||||:||.|||.::||.|:.|                 .:|:|.|:.:...|
Human   119 LSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAIGPWQVAVPHIPLFPWQETEELEEEKSGL 183

  Fly   248 KNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLSELELETVSIDGPNSGNNNQR 312
            :.::.:|:.|::||..||.:||    ..|::..:..:||....|..:          .||
Human   184 QKEIAELQKEKEKLEFMLVAHG----PVCKISPEERRSPPAPGLQPM----------RSG----- 229

  Fly   313 LQSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQ--------------QQQ 363
                        |....|.:.:|.|.....||.|:     ||..:.|:              ::.
Human   230 ------------GGSVGAVVVKQEPLEEDSPSSSS-----AGLDKAQRSVIKPISIAGGFYGEEP 277

  Fly   364 QQQP------QSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGSASNHPSHNNNNNNNNSSGA 422
            ...|      .::.|..:|::...     ||:|....|        ||...|.:..:..::|||.
Human   278 LHTPIVVTSTPAVTPGTSNLVFTY-----PSVLEQESP--------ASPSESCSKAHRRSSSSGD 329

  Fly   423 SSNTSNNNSNI 433
            .|:.|.|:..:
Human   330 QSSDSLNSPTL 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	21/69 (30%)
		coiled coil	215..265	CDD:269870	19/66 (29%)
FOSL2	XP_006712039.1	bZIP_Fos	134..204	CDD:269869	21/69 (30%)
		coiled coil	134..203	CDD:269869	21/68 (31%)