Protein Alignment Atf3 and Fosb

DIOPT Version :10

• Sequence 1: NP_001259125.1
• Gene: Atf3 / 43867
• FlyBaseID: FBgn0028550
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_032062.1
• Gene: Fosb / 14282
• MGIID: 95575
• Length: 338
• Species: Mus musculus
• Alignment Length: 420
• Identity: 89/420 - (21%)
• Similarity: 152/420 - (36%)
• Gaps: 148/420 - (35%)

  Fly    39 TNPLENFSYSSAAAAAAAVSVASSSASCS------AASTPVVTVRHFNGHPNGQSHSQD------ 91
            ::|.....|.|:..:..:...|::|..|:      .:..|.||         ..:.|||
Mouse    17 SSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVT---------AITTSQDLQWLVQ 72

  Fly    92 ----SSHSSCSGSPL----------DSPAGTATTPSVQQTCSRLIKEGLKLSIQSKRKLSTCDSS 142
                ||.:...|.||          |.|..:.:||.:
Mouse    73 PTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGL---------------------------- 109

  Fly   143 SGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEESSDDDSETKSQPK-----GLTP 202
                   |.||...::.:|...:|...||.:|               ....:::|:     .|||
Mouse   110 -------SAYSTGGASGSGGPSTSTTTSGPVS---------------ARPARARPRRPREETLTP 152

  Fly   203 EDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKS 267
            |:|::||.||||||:||.|||.::||.|..|..|::.|:.:..||::::.:|:.|:::|..:|.:
Mouse   153 EEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVA 217

  Fly   268 HGCQRAGGCQLPSQLLQSPAQKYLSELELETVSIDGPNSGNNNQRLQSIPSMATFK---YGSKTA 329
            |    ..||::|.:                    :||..|...: ::.:|...:.|   :|....
Mouse   218 H----KPGCKIPYE--------------------EGPGPGPLAE-VRDLPGSTSAKEDGFGWLLP 257

  Fly   330 AAMAQQLPNGYCKPSP---SAQEFEHAGYQQQQQQQQQQQPQSLNPAGNNVIDQQHANPSPSLLS 391
            ......||....:.:|   :|..|.|:..|                    |:.......|||..|
Mouse   258 PPPPPPLPFQSSRDAPPNLTASLFTHSEVQ--------------------VLGDPFPVVSPSYTS 302

  Fly   392 DYVPNCDGLTG-------SASNHPSHNNNN 414
            .:|..|..::.       |.|..||...|:
Mouse   303 SFVLTCPEVSAFAGAQRTSGSEQPSDPLNS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	19/52 (37%)
		coiled coil	215..265	CDD:269870	18/49 (37%)
Fosb	NP_032062.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		6/36 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..179		35/148 (24%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	157..182		16/24 (67%)
		bZIP_Fos	165..218	CDD:269869	19/52 (37%)
		coiled coil	165..217	CDD:269869	19/51 (37%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	183..211		7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	222..276		11/74 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..338		5/17 (29%)